share:
delim
Medical Marijuana
Growing Analytical Solutions
for Medical Cannabis Labs

  • Restek is an industry leader in new chromatography products and emerging applications.
  • We offer a full line of GC and LC supplies for accurate, reliable medical cannabis analyses.
  • Your continued success is our goal—we provide expert support for both startups and established labs.
Growing Analytical Solutions for Medical Cannabis Labs

Whether you are an experienced potency testing chemist or a manager starting up a new lab, Restek has the products and expertise you need for successful medical cannabis analyses. We’ve been committed to this emerging industry from its humble beginnings through its recent years of rapid growth. During that time, we produced the first technical literature on potency testing in the business, and our experts continue to provide cutting-edge scientific support and a comprehensive line of products for new tests as they emerge. From analyzing potency and pesticides by LC, to testing for terpenes and residual solvents by GC, Restek offers the chromatography columns, accessories, and sample preparation supplies that you need for accurate, reliable medical marijuana analyses. In addition, we have the most comprehensive selection of cannabinoid-related certified reference materials (CRMs), manufactured and QC tested in our ISO-accredited laboratories.

We’re proud to have helped medical cannabis labs establish sound analytical practices from the beginning, and we will continue to be there for you every step of the way as the testing landscape changes. Explore our products and resources and grow your medical cannabis testing business with analytical solutions from Restek!

Restek Expertise & Service

Our commitment to medical marijuana analysis extends beyond a trusted, well-rounded product line. If you're struggling with any part of your cannabinoid analyses, contact us—we’re here to help!

Restek Technical Service
1-814-353-1300, ext. 4 | support@restek.com

Columns

Rxi-35Sil MS Columns (fused silica)

midpolarity Crossbond phase

  • Special selectivity and excellent inertness for substituted polar compounds, such as drugs, pesticides, herbicides, PCBs, phenols, etc.
  • Provides superior separation for cannabinoids.
  • Very low-bleed phase for GC-MS analysis.
  • Extended temperature range: 50 °C up to 360 °C.

Rxi-624Sil MS Columns (fused silica)

midpolarity Crossbond phase

  • Low-bleed, high-thermal stability column—maximum temperatures up to 300–320 °C.
  • Inert—excellent peak shape for a wide range of compounds.
  • Selective—G43 phase highly selective for volatile organics and residual solvents, great choice for USP<467>.
  • Manufactured for column-to-column reproducibility—well suited for validated methods.

Rxi-5Sil MS Columns (fused silica)

low-polarity phase; Crossbond 1,4-bis(dimethylsiloxy)phenylene dimethyl polysiloxane

  • Engineered to be a low-bleed GC-MS column.
  • Excellent inertness for active compounds.
  • General-purpose columns—ideal for GC-MS analysis of semivolatiles, polycyclic aromatic compounds, chlorinated hydrocarbons, phthalates, phenols, amines, organochlorine pesticides, organophosphorus pesticides, drugs, solvent impurities, and hydrocarbons.
  • Temperature range: -60 °C to 350 °C.

Rxi Guard/Retention Gap Columns (fused silica)

  • Extend column lifetime.
  • Excellent inertness—obtain lower detection limits for active compounds.
  • Sharper chromatographic peaks by utilizing retention gap technology.
  • Maximum temperature: 360 °C.

Raptor ARC-18 LC Columns (USP L1)

  • Ideal for high-throughput LC-MS/MS applications with minimal sample preparation.
  • Well-balanced retention profile for better detection and integration of large, multiclass analyte lists.
  • Sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality.
  • Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica.

Ultra Aqueous C18 Columns (USP L1)

Particle Size: 3 µm or 5 µm, spherical
Pore Size: 100 Å
Carbon Load: 15%
End-Cap: no
pH Range: 2.5 to 8
Temperature Limit: 80 °C
USP Phase Code: L1
Phase Category: modified C18
Ligand Type: proprietary polar modified and functionally bonded C18

Reference Standards

Medical Cannabis Standards

Comprehensive suite of certified reference materials developed specifically for medical
marijuana analysis.

QuEChERS Internal Standards and Quality Control Standards

  • Single and multiple component standards as specified in EN Method 15662.
  • Support for GC and HPLC with MS, MS/MS, and selective detectors.
  • Ready to use for QuEChERS extractions—no dilutions necessary.

Sample Handling

Q-sep QuEChERS dSPE Tubes for Extract Cleanup

Fast, Simple Sample Prep for Multiresidue Pesticide Analysis

  • Packaged in foil subpacks of 10 for enhanced protection and storage stability.
  • Ready-to-use tubes, no glassware required.
  • Pre-weighed, ultra-pure sorbents.
  • Support original unbuffered, AOAC (2007.01), European (EN 15662), and mini-multiresidue QuEChERS methods.

Q-sep 3000 Centrifuge

for QuEChERS

  • Supports 50 mL, 15 mL, and 2 mL centrifuge tubes.
  • Small footprint requires less bench space.
  • Safe and reliable—UL, CSA, and CE approved; 1-year warranty.

Q-sep Tube Racks

  • Available for 2 mL, 15 mL, and 50 mL tubes.
  • Alphanumerical grid reference on top tier for easy identification of samples.
  • Easy to assemble; simply fold and snap together securely.

Pesticide Residue Cleanup SPE Cartridges

  • Convenient, multiple adsorbent beds in a single cartridge.
  • For use in multiresidue pesticide analysis to remove matrix interferences.
  • Excellent for cleanup of dietary supplement extracts.

Resprep SPE Cartridges (Bonded Reversed Phases)

Hydrophobic (nonpolar) silica-based adsorbents; used to extract hydrophobic analytes from polar matrices, such as water (e.g., pesticides from water).

C18 (high load, endcapped)

Supplies & Accessories

LC Multiresidue Pesticide Kit

  • Accurately detect and quantify pesticides of global food safety concern in a wide range of fruits, vegetables, and other commodities by LC-MS/MS.
  • Full kit contains 204 compounds of interest, covering many LC-determined pesticides listed by government agencies; individual ampuls also sold separately.

GC Multiresidue Pesticide Kit

  • Accurately identify and quantify pesticide residues by GC-MS/MS in fruits, vegetables, botanicals, and herbals such as tea, ginseng, ginger, echinacea, and dietary supplements.
  • Comprehensive 203-compound kit covers food safety lists by the FDA, USDA, and other global governmental agencies; individual ampuls also sold separately.

Topaz Inlet Liners for Bruker/Varian Instruments

Topaz Inlet Liners for DANI Instruments

Topaz Inlet Liners for PerkinElmer Instruments

Topaz Inlet Liners for Shimadzu Instruments

Topaz Inlet Liners for Thermo Scientific TRACE and Focus Instruments

Topaz Inlet Liners for Thermo Scientific TRACE 1300, 1310 Instruments

GC Accessories

Full line of GC consumables, lab tools to make your life easier, and replacement parts for all major instrument manufacturers.

LC Accessories

Quality replacement parts, tools, and accessories for liquid chromatography.

2.0 mL, 8 mm Autosampler Vial Convenience Kits

Vials packaged in a clear-lid tray. Preassembled caps with septa packaged separately in a plastic bag.

Manual Microliter Syringes (Hamilton 700 Series)

  • Economical.
  • Available with cemented needles (N/F) or removable needles (RN/R).
  • Each syringe plunger and barrel assembly is manufactured as one working unit; components are not interchangeable or individually replaceable.

ChromaBLOGraphy
posted Mon, Apr 27, 2015
Residual Solvents in Cannabis – to MS or not to MS?
posted Wed, Jan 14, 2015
CBDV and THCV on the Rxi-35Sil MS GC Column with Other Cannabinoids
posted Fri, Jan 16, 2015
Internal Standard versus External Standard Quantification in Medical Cannabis Potency Analysis with GC-FID
posted Thu, Feb 05, 2015
Optimization of Cannabis Analyses from the Emerald Conference
posted Fri, Jun 14, 2013
The separation problem with CBC and CBD in GC analysis of medical cannabis with 5% phenyl-type columns.
posted Sun, Feb 17, 2013
Don’t overestimate cannabidiol during medical cannabis potency determinations with gas chromatography. Use stationary phase selectivity for accuracy and hydrogen for fast analysis.
posted Sun, May 20, 2012
Screening for Bifenazate (Floramite) in Medical Marijuana Using QuEChERS and GC-FID – Is it Possible?
posted Fri, Apr 20, 2012
Medical Marijuana Musings
posted Wed, Aug 03, 2011
Medical Marijuana Solvent Extraction Efficiency – Potency Determinations with GC-FID
posted Sat, Jul 30, 2011
The Impact of a Dirty Marijuana Extract on Pesticide Recoveries from a Splitless GC Inlet
posted Fri, Jul 29, 2011
Thiabendazole – Planar Pesticide Loss to Graphitized Carbon Black during Dispersive Solid Phase Extraction Cleanup for QuEChERS
posted Sat, Jul 02, 2011
The Bard Hits the Bong?
posted Sun, May 22, 2011
High Quality Analysis of Pesticides in Marijuana using QuEChERS, Cartridge SPE Cleanup, and GCxGC-TOFMS
posted Wed, Apr 20, 2011
First QuEChERS Extraction of Marijuana with GCxGC-TOFMS Analysis, dudes…
View all our medical cannabis blogs...

Literature

Foods, Flavors & Fragrances

Featured Application: Cannabinoid Profiles on Raptor ARC-18 - High-Throughput Analysis of Cannabinoids by LC-UV

This simple, isocratic LC-UV analysis of cannabinoids provides complete resolution of 16 cannabinoids, allowing accurate quantitative potency and profile data to be reported. All compounds are separated to baseline in a fast, 9-minute analysis, making this method suitable for high-throughput cannabis testing labs.

Clinical, Forensic & Toxicology

Analysis of Synthetic Cannabinoids and Metabolites: Adding New Compounds to an Existing LC-MS/MS Method

The analysis of synthetic cannabinoids and their metabolites can be a difficult and challenging task. Keeping up with the ever-growing list of synthetic cannabinoids that illicit drug makers produce further complicates the analysis. As shown here, the retention and selectivity of the Raptor Biphenyl column allows new drugs to be added to an existing method, providing labs with an important vehicle for improving efficiency and productivity.
Foods, Flavors & Fragrances

High-Quality Analysis of Pesticides in Cannabis Using QuEChERS, Cartridge SPE Cleanup, and GCxGC-TOFMS

As medical marijuana is more frequently prescribed, patient safety must be ensured. Pesticide residue testing is an important part of assuring safe product is dispensed, but analysis can be extremely challenging due to matrix complexity. The use of QuEChERS, cartridge SPE cleanup, and GCxGC-TOFMS as presented here produces high-quality quantitative data for this difficult analysis.
Foods, Flavors & Fragrances

Comprehensive Pesticide Residue Analysis by LC-MS/MS Using an Ultra Aqueous C18 Column

Analysis of pesticide residues in foods is complicated by the large number of target compounds. LC-MS/MS analysis using an Aqueous C18 column provides more comprehensive results than GC alone.
PDF Document

High Quality Analysis of Pesticides in Marijuana for Medicine Using QuEChERS, Cartridge SPE Cleanup, and GCxGC - TOFMS

Review our Pittcon presentation on the analysis of pesticides in marijuana. Here we demonstrate that complex cannabis samples can be effectively prepared for chromatographic analysis using QuEChERS and cartridge SPE. GCxGC was used to separate pesticides that would coelute with matrix interferences in one-dimensional GC. (PDF - 0MB)
PDF Document

Growing Analytical Solutions for Cannabis Testing

Restek has been helping cannabis labs establish innovative, cost-effective analytical solutions from the very beginning. We have the GC and LC products and expertise you need today for analyzing potency, terpenes, residual solvents, and pesticide residues. And we are developing the products you’ll need tomorrow for emerging cannabis applications in this fast-growing industry. (PDF - 0MB)
PDF Document

Accurately Quantify 380 Pesticides Using LC-MS/MS and GC-MS/MS

Stop spending your time and money developing LC-MS/MS or GC-MS/MS multiresidue pesticide methods and mixing reference standards when you could be running samples. Restek’s expert formulations chemists and chromatographers have already done the work for you—with guaranteed accuracy and at a lower cost. (PDF - 0MB)

GC Chromatograms

General Interest

Cannabinoids on Rxi®-35Sil MS Using Hydrogen Carrier Gas by GC-FID

GC_FS0501

Foods, Flavors & Fragrances

QuEChERS Extract of Cannabis on Rxi®-17Sil MS and Rxi®-5ms by GCxGC-TOFMS

GC_FF1207

Foods, Flavors & Fragrances

QuEChERS Extract of Cannabis on Rxi®-17Sil MS and Rxi®-5ms by GCxGC-TOFMS (Zoomed in on terpenes region)

GC_FF1208

Foods, Flavors & Fragrances

QuEChERS Extract of Cannabis on Rxi®-17Sil MS and Rxi®-5ms by GCxGC-TOFMS (Zoomed in on cannabinoids region)

GC_FF1209

General Interest

GC Potency Analysis for Marijuana on Rxi®-5Sil MS

GC_GN1156

Foods, Flavors & Fragrances

Tebuthiuron in a QuEChERS Extract of Marijuana by GCxGC on Rxi®-5Sil MS and Rtx®-200

GC_FF1202

Foods, Flavors & Fragrances

Incurred Cypermethrins in a QuEChERS Extract of Marijuana by GCxGC on Rxi®-5Sil MS and Rtx®-200

GC_FF1203

Foods, Flavors & Fragrances

Incurred Cypermethrins in a QuEChERS Extract of Marijuana by GCxGC on Rxi®-5Sil MS and Rtx®-200

GC_FF1204

Foods, Flavors & Fragrances

Marijuana Pesticides by GCxGC on Rxi®-5Sil MS and Rtx®-200

GC_FF1205

Foods, Flavors & Fragrances

Sample and Reference Mass Spectra for Incurred Cypermethrin in a QuEChERS Extract of Marijuana by GCxGC on Rxi®-5Sil MS and Rtx®-200

GC_FF1206

Foods, Flavors & Fragrances

Cannabinoids in Cannabis Sample 94 on Rxi®-35Sil MS

GC_FS0527

Foods, Flavors & Fragrances

Cannabinoids in Cannabis Sample 10 on Rxi®-35Sil MS

GC_FS0528

Foods, Flavors & Fragrances

Medical Cannabis Terpenes on Rxi®-624Sil MS by FET-HS-GC

GC_FS0518

Foods, Flavors & Fragrances

Terpene Profile of Cascade Hops on Rxi®-624Sil MS by FET-HS-GC

GC_FS0523

Foods, Flavors & Fragrances

Terpenes in Kryptonite Medical Cannabis on Rxi®-624Sil MS

GC_FS0510

Foods, Flavors & Fragrances

Terpenes in Blueberry Jack Medical Cannabis on Rxi®-624Sil MS

GC_FS0511

General Interest

Residual Solvents in Cannabis Concentrates on Rxi®-624Sil MS by Headspace–Full Evaporation Technique (HS-FET)

GC_FS0563