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Featured Literature

Ultra II™ LC Columns: The Column Line Designed for Optimal Chromatography on ANY LC System, Based on Highly Inert Restek Silica

Ultra II™ is the first LC column line specifically designed for universal application and completely scalable chromatography, from conventional to ultra-high pressure systems. Available in a wide range of phases, including traditional and unique chemistries.
lit. cat.# GNTS1177 (393kb PDF)

Resolution Evolution: Biphenyl—Next Generation of Phenyl Columns

Biphenyl columns provide both high hydrophobic retention and aromatic selectivity in the same column. Orthogonal separations can be achieved with simple mobile phase changes, giving markedly better separations for a wide variety of molecules.
lit. cat.# GNFL1096 (523kb PDF)

LC/MS/MS System Suitability Test Mix for Drug Analysis
Analytical Reference Materials

< Tear Sheet

Ensure proper LC/MS/MS system function by analyzing a system suitability mix on a regular basis. This mix contains compounds covering a wide range of masses and polarities, and a simple test is used to evaluate the entire analytical system.
lit. cat.# CFTS1002 (160kb PDF)

Identification of Cocaine Adulterants Using GC and HPLC

< Application Note

GC and LC methods can be used to “fingerprint” cocaine samples for law enforcement purposes. Here we show the analysis of simulated cocaine samples by both techniques and give column and instrument conditions for successful analysis.
lit. cat.# 580033 (294kb PDF)

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Featured Articles

LC/MS/MS Analysis of Diuretics in Urine:
Proper Column Choice Takes Matrix out of the Equation

< Added October 2009

Ultra II™ Biphenyl columns improve the accuracy of diuretics analysis in urine by separating target diuretics from isobaric matrix interferences. Fast, reliable separation can be achieved for compounds that coelute on phenyl hexyl columns.
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Reduce Downtime and Cost of Materials with Rugged Rxi®-5Sil MS GC Columns

< Added July 2009

New Rxi®-5Sil MS columns produce consistent results for amphetamine—even after 400 injections of derivatizing reagent—resulting in less time and money spent on column maintenance and replacement.
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High Sensitivity EtG and EtS Method Reduces Costs and Analysis Time

< Added July 2009

A new LC method for analyzing ethanol metabolites using ion-pairing provides higher retention, faster analysis times, and improved MS sensitivity for EtG and EtS, compared to conventional methods.
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5 Minute Analysis of Vitamin D in Serum by LC/MS/MS

Conventional techniques for vitamin D analysis often lack adequate sensitivity, specificity, and speed. This LC/MS/MS assay results in highly symmetric peaks that elute in just 5 minutes.
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Fast, Sensitive Analysis of Benzodiazepines by LC/MS/MS

An LC/MS/MS method for benzodiazepines with several advantages over other techniques: minimal sample preparation, fast analysis times, multiple reaction monitoring transitions for quantification and confirmation, and sensitivity down to 0.10-10ng/mL.
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