Topics in GC & HPLC

Everybody knows that column cutting is important. For some injection techniques, its more important then for others. With a split-injection we usually get away easy. With on-column and direct injection the challenge is bigger. Also, If we want to make coupling, we need an ideal cut. Fused silica can be cut with different devices, of which the “wafer” is the most simple and the cheapest..

Cutting metal (MXT) columns is another story. When using a split injection one may use the wafer:most of the time MXT columns are used with Valves, on-column injection or a PTV type injection

To reduce dead volumes in these systems, one needs the best column cut. A device to help us, has become available. Its called a column “scorer”. By scoring the MXT tubing on the outside, trimming becomes easy and a perfect end cut is created, allowing:

- no issues with on-column injection

- the best possible “seal” using direct injection liners (PTV)

- minimal dead volume in Valve connections