delim
Medical Marijuana
Growing Analytical Solutions
for Medical Cannabis Labs

  • Restek is an industry leader in new chromatography products and emerging applications.
  • We offer a full line of GC and LC supplies for accurate, reliable medical cannabis analyses.
  • Your continued success is our goal—we provide expert support for both startups and established labs.
Growing Analytical Solutions for Medical Cannabis Labs

Whether you are an experienced potency testing chemist or a manager starting up a new lab, Restek has the products and expertise you need for successful medical cannabis analyses. We’ve been committed to this emerging industry from its humble beginnings through its recent years of rapid growth. During that time, we produced the first technical literature on potency testing in the business, and our experts continue to provide cutting-edge scientific support and a comprehensive line of products for new tests as they emerge. From analyzing potency and pesticides by LC, to testing for terpenes and residual solvents by GC, Restek offers the chromatography columns, accessories, and sample preparation supplies that you need for accurate, reliable medical marijuana analyses. In addition, we have the most comprehensive selection of cannabinoid-related certified reference materials (CRMs), manufactured and QC tested in our ISO-accredited laboratories.

We’re proud to have helped medical cannabis labs establish sound analytical practices from the beginning, and we will continue to be there for you every step of the way as the testing landscape changes. Explore our products and resources and grow your medical cannabis testing business with analytical solutions from Restek!

Restek Expertise & Service

Our commitment to medical marijuana analysis extends beyond a trusted, well-rounded product line. If you're struggling with any part of your cannabinoid analyses, contact us—we’re here to help!

Julie Kowalski Julie Kowalski
Biography | Contact
Restek Technical Service
1-814-353-1300, ext. 4 | support@restek.com

Columns

Rxi-35Sil MS Columns (fused silica)

midpolarity Crossbond phase

  • Special selectivity and excellent inertness for substituted polar compounds, such as drugs, pesticides, herbicides, PCBs, phenols, etc.
  • Provides superior separation for cannabinoids.
  • Very low-bleed phase for GC-MS analysis.
  • Extended temperature range: 50 °C up to 360 °C.

Rxi-624Sil MS Columns (fused silica)

midpolarity Crossbond phase

  • Low-bleed, high-thermal stability columnmaximum temperatures up to 300320 °C.
  • Inertexcellent peak shape for a wide range of compounds.
  • SelectiveG43 phase highly selective for volatile organics and residual solvents, great choice for USP<467>.
  • Manufactured for column-to-column reproducibilitywell suited for validated methods.

Rxi-5Sil MS Columns (fused silica)

low-polarity phase; Crossbond 1,4-bis(dimethylsiloxy)phenylene dimethyl polysiloxane

  • Engineered to be a low-bleed GC-MS column.
  • Excellent inertness for active compounds.
  • General-purpose columnsideal for GC-MS analysis of semivolatiles, polycyclic aromatic compounds, chlorinated hydrocarbons, phthalates, phenols, amines, organochlorine pesticides, organophosphorus pesticides, drugs, solvent impurities, and hydrocarbons.
  • Temperature range: -60 °C to 350 °C.

Rxi Guard/Retention Gap Columns (fused silica)

  • Extend column lifetime.
  • Excellent inertnessobtain lower detection limits for active compounds.
  • Sharper chromatographic peaks by utilizing retention gap technology.
  • Maximum temperature: 360 °C.

Raptor ARC-18 LC Columns (USP L1)

  • Ideal for high-throughput LC-MS/MS applications with minimal sample preparation.
  • Well-balanced retention profile for better detection and integration of large, multiclass analyte lists.
  • Sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality.
  • Part of Restek’s Raptor LC column line featuring 2.7 and 5 µm SPP core-shell silica.

Ultra Aqueous C18 Columns (USP L1)

Particle Size: 3 µm or 5 µm, spherical
Pore Size: 100 Å
Carbon Load: 15%
End-Cap: no
pH Range: 2.5 to 8
Temperature Limit: 80 °C
USP Phase Code: L1
Phase Category: modified C18
Ligand Type: proprietary polar modified and functionally bonded C18

Reference Standards

Medical Cannabis Standards

Comprehensive suite of certified reference materials developed specifically for medical
marijuana analysis.

QuEChERS Internal Standards and Quality Control Standards

  • Single and multiple component standards as specified in EN Method 15662.
  • Support for GC and HPLC with MS, MS/MS, and selective detectors.
  • Ready to use for QuEChERS extractions—no dilutions necessary.

Sample Handling

Q-sep QuEChERS Extraction Salts

Fast, Simple Sample Prep for Multiresidue Pesticide Analysis

  • Salt packets eliminate the need for a second empty tube to transfer salts.
  • Go green by using packets with reusable tubes.
  • Convenient and easy to use.
  • Ready-to-use tubes, no glassware required.
  • Preweighed, ultra-pure sorbents.
  • Support original unbuffered, AOAC (2007.01) and European (EN 15662) QuEChERS methods.

Q-sep QuEChERS dSPE Tubes for Extract Cleanup

Fast, Simple Sample Prep for Multiresidue Pesticide Analysis

  • Packaged in foil subpacks of 10 for enhanced protection and storage stability.
  • Ready-to-use tubes, no glassware required.
  • Preweighed, ultra-pure sorbents.
  • Support original unbuffered, AOAC (2007.01), European (EN 15662), and mini-multiresidue QuEChERS methods.

Q-sep 3000 Centrifuge

for QuEChERS

  • Meets or exceeds requirements of original unbuffered, AOAC, and European QuEChERS methodology.
  • Supports 50 mL, 15 mL, and 2 mL centrifuge tubes.
  • Small footprint requires less bench space.
  • Safe and reliableUL, CSA, and CE approved; 1-year warranty.

Q-sep Tube Racks

  • Available for 2 mL, 15 mL, and 50 mL tubes.
  • Alphanumerical grid reference on top tier for easy identification of samples.
  • Easy to assemble; simply fold and snap together securely.

Pesticide Residue Cleanup SPE Cartridges

  • Convenient, multiple adsorbent beds in a single cartridge.
  • For use in multiresidue pesticide analysis to remove matrix interferences.
  • Excellent for cleanup of dietary supplement extracts.

Resprep SPE Cartridges (Bonded Reversed Phases)

Hydrophobic (nonpolar) silica-based adsorbents; used to extract hydrophobic analytes from polar matrices, such as water (e.g., pesticides from water).

C18 (high load, endcapped)

Supplies & Accessories

LC Multiresidue Pesticide Kit

  • Accurately detect and quantify pesticides of global food safety concern in a wide range of fruits, vegetables, and other commodities by LC-MS/MS.
  • Full kit contains 204 compounds of interest, covering many LC-determined pesticides listed by government agencies; individual ampuls also sold separately.

GC Multiresidue Pesticide Kit

  • Accurately identify and quantify pesticide residues by GC-MS/MS in fruits, vegetables, botanicals, and herbals such as tea, ginseng, ginger, echinacea, and dietary supplements.
  • Comprehensive 203-compound kit covers food safety lists by the FDA, USDA, and other global governmental agencies; individual ampuls also sold separately.

Cannabidiolic Acid (CBDA) Standard

  • U.S. Drug Enforcement Agency (DEA)-exempted preparation—no need to purchase costly neat materials or to make your own standards.
  • Pair with Restek's THC standards to analyze both neutrals and acids in cannabis products by LC.
  • A must for accurate quantification in medical cannabis potency testing and strain ID.
  • Prepared in acetonitrile, instead of methanol, to maintain stability and prevent methylation of carboxylic acid groups.

Merlin MicroShot Injector

  • NIST traceability assures accurate injections.
  • Fixed volume reduces sampling error.
  • Saves timeno need to transfer to autosampler vials.
  • Prevents bent syringe plungers.
  • Five injection volumes available.*

Sky® Inlet Liners

Exceptionally inert Sky® inlet liners with in situ deactivated wool are ideal for GC analysis of medical cannabis samples.


Sky® 4.0 mm ID Single Taper Inlet Liner w/ Wool
Sky® 4.0 mm ID Precision® Inlet Liner w/ Wool

GC Accessories

Full line of GC consumables, lab tools to make your life easier, and replacement parts for all major instrument manufacturers.

LC Accessories

Quality replacement parts, tools, and accessories for liquid chromatography.

2.0 mL, 8 mm Autosampler Vial Convenience Kits

Vials packaged in a clear-lid tray. Preassembled caps with septa packaged separately in a plastic bag.

Manual Microliter Syringes (Hamilton 700 Series)

  • Economical.
  • Available with cemented needles (N/F) or removable needles (RN/R).
  • Each syringe plunger and barrel assembly is manufactured as one working unit; components are not interchangeable or individually replaceable.

ChromaBLOGraphy

posted Mon, Apr 27, 2015
Residual Solvents in Cannabis – to MS or not to MS?
posted Wed, Jan 14, 2015
CBDV and THCV on the Rxi-35Sil MS GC Column with Other Cannabinoids
posted Fri, Jan 16, 2015
Internal Standard versus External Standard Quantification in Medical Cannabis Potency Analysis with GC-FID
posted Thu, Feb 05, 2015
Optimization of Cannabis Analyses from the Emerald Conference
posted Fri, Jun 14, 2013
The separation problem with CBC and CBD in GC analysis of medical cannabis with 5% phenyl-type columns.
posted Sun, Feb 17, 2013
Don’t overestimate cannabidiol during medical cannabis potency determinations with gas chromatography. Use stationary phase selectivity for accuracy and hydrogen for fast analysis.
posted Sun, May 20, 2012
Screening for Bifenazate (Floramite) in Medical Marijuana Using QuEChERS and GC-FID – Is it Possible?
posted Fri, Apr 20, 2012
Medical Marijuana Musings
posted Wed, Aug 03, 2011
Medical Marijuana Solvent Extraction Efficiency – Potency Determinations with GC-FID
posted Sat, Jul 30, 2011
The Impact of a Dirty Marijuana Extract on Pesticide Recoveries from a Splitless GC Inlet
posted Fri, Jul 29, 2011
Thiabendazole – Planar Pesticide Loss to Graphitized Carbon Black during Dispersive Solid Phase Extraction Cleanup for QuEChERS
posted Sat, Jul 02, 2011
The Bard Hits the Bong?
posted Sun, May 22, 2011
High Quality Analysis of Pesticides in Marijuana using QuEChERS, Cartridge SPE Cleanup, and GCxGC-TOFMS
posted Wed, Apr 20, 2011
First QuEChERS Extraction of Marijuana with GCxGC-TOFMS Analysis, dudes…
View all our medical cannabis blogs...

Literature

Foods, Flavors & Fragrances

A Fast, Simple FET Headspace GC-FID Technique for Determining Residual Solvents in Cannabis Concentrates

As the cannabis industry expands, demand is increasing for analysis of residual solvents in cannabis concentrates in order to protect consumer safety. This application note details a simple, fast, accurate test for common residual solvents using full evaporation technique headspace GC-FID and an Rxi®-624Sil MS column.

Foods, Flavors & Fragrances

A Preliminary FET Headspace GC-FID Method for Comprehensive Terpene Profiling in Cannabis

This application note describes an FET-HS-GC-FID method that was developed in hops for the analysis of terpenes in cannabis. Good chromatographic separation allowed quantification of critical compounds across the volatility range, including α-pinene, β-myrcene, α-humulene, β-caryophyllene, and caryophyllene oxide.

Foods, Flavors & Fragrances

High-Quality Analysis of Pesticides in Cannabis Using QuEChERS, Cartridge SPE Cleanup, and GCxGC-TOFMS

As medical marijuana is more frequently prescribed, patient safety must be ensured. Pesticide residue testing is an important part of assuring safe product is dispensed, but analysis can be extremely challenging due to matrix complexity. The use of QuEChERS, cartridge SPE cleanup, and GCxGC-TOFMS as presented here produces high-quality quantitative data for this difficult analysis.

Foods, Flavors & Fragrances

Don’t Overestimate Cannabidiol During Medical Cannabis Potency Testing by Gas Chromatography

Proper GC column choice is essential for accurate and robust medical cannabis potency testing. Using an Rxi-35Sil MS column under the instrument conditions shown here allows fast, accurate reporting of cannabichromene and cannabidiol in medical marijuana samples.

Foods, Flavors & Fragrances

Comprehensive Pesticide Residue Analysis by LC-MS/MS Using an Ultra Aqueous C18 Column

Analysis of pesticide residues in foods is complicated by the large number of target compounds. LC-MS/MS analysis using an Aqueous C18 column provides more comprehensive results than GC alone.

PDF Document

High Quality Analysis of Pesticides in Marijuana for Medicine Using QuEChERS, Cartridge SPE Cleanup, and GCxGC - TOFMS

Review our Pittcon presentation on the analysis of pesticides in marijuana. Here we demonstrate that complex cannabis samples can be effectively prepared for chromatographic analysis using QuEChERS and cartridge SPE. GCxGC was used to separate pesticides that would coelute with matrix interferences in one-dimensional GC. (PDF - 8MB)

PDF Document

Growing Analytical Solutions for Cannabis Testing

Restek has been helping cannabis labs establish innovative, cost-effective analytical solutions from the very beginning. We have the GC and LC products and expertise you need today for analyzing potency, terpenes, residual solvents, and pesticide residues. And we are developing the products you’ll need tomorrow for emerging cannabis applications in this fast-growing industry. (PDF - 7MB)

PDF Document

Accurately Quantify 380 Pesticides Using LC-MS/MS and GC-MS/MS

Stop spending your time and money developing LC-MS/MS or GC-MS/MS multiresidue pesticide methods and mixing reference standards when you could be running samples. Restek’s expert formulations chemists and chromatographers have already done the work for you—with guaranteed accuracy and at a lower cost. (PDF - 6MB)

GC Chromatograms

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