delim
Clinical, Forensic & Toxicology Solutions

Clinical, Forensic & Toxicology Solutions

Rtx®-BAC Plus 1 Columns (fused silica)

  • Optimized column selectivities guarantee resolution of ethanol, internal standards, and frequently encountered interferences.
  • Robust and reproducible column chemistry ensures longer column lifetime and consistent results.
  • 2 minute analysis time increases lab productivity.
  • Stable to 260 °C

    Don’t forget: Blood alcohol analysis requires dual column confirmation when using GC/FID. Click here for information on the secondary column for this application.

Rtx®-BAC Plus 2 Columns (fused silica)

  • Optimized column selectivities guarantee resolution of ethanol, internal standards, and frequently encountered interferences.
  • Robust and reproducible column chemistry ensures longer column lifetime and consistent results.
  • 2 minute analysis time increases lab productivity.
  • Stable to 260 °C

    Don’t forget: Blood alcohol analysis requires dual column confirmation when using GC/FID. Click here for information on the primary column for this application.

BAC Resolution Control Standard n-P (6 components)

  • Use to verify the retention time for each compound normally included in a blood alcohol test, and to verify that the compounds are resolved from and do not interfere with one another.
  • Includes 1-propanol internal standard.
  • Intended for qualitative use only.

BAC Resolution Control Standard t-B (6 components)

  • Use to verify the retention time for each compound normally included in a blood alcohol test, and to verify that the compounds are resolved from and do not interfere with one another.
  • Includes tert-butanol internal standard.
  • Intended for qualitative use only.
  • Also available: blood alcohol standards for calibration.

Pinnacle® DB Biphenyl Columns (USP L11)

particle size: 1.9µm, 3µm, or 5µm, spherical
pore size: 140Å
carbon load: 8%
endcap: yes
pH range: 2.5 to 8
temperature limit: 80°C

Pinnacle® DB Biphenyl is a unique reversed phase material that displays both increased retention and selectivity for aromatic and/or unsaturated compounds when compared to conventional alkyl and phenyl phases. Highly base-deactivated spherical silica manufactured by Restek. An excellent choice for the analysis of steroids, tetracyclines, drug metabolites, and other compounds that contain some degree of unsaturation. Part of the Restek USLC™ column set, which offers the widest range of reversed phase selectivity available!

Ultra Biphenyl Columns (USP L11)

particle size: 3µm or 5µm, spherical
pore size: 100Å
carbon load: 15%
endcap: fully endcapped
pH range: 2.5 to 8
temperature limit: 80°C

A unique reversed phase material that exhibits both increased retention and selectivity for aromatic and/or unsaturated compounds, compared to conventional alkyl and phenyl phases. This is a great alternative to a C18 column when alternative selectivity is desired. An excellent choice for the analysis of steroids, tetracyclines, drug metabolites, and other compounds that contain some degree of unsaturation. Part of the Restek USLC™ column set, which offers the widest range of reversed phase selectivity available!

Rxi®-5Sil MS Columns (fused silica)

(low polarity Crossbond® silarylene phase; similar to 5% phenyl/95% dimethyl polysiloxane)

  • Engineered to be a low bleed GC/MS column.
  • Excellent inertness for active compounds.
  • General purpose columns—ideal for GC/MS analysis of polycyclic aromatic compounds, chlorinated hydrocarbons, phthalates, phenols, amines, organochlorine pesticides, organophosphorus pesticides, drugs, solvent impurities, and hydrocarbons.
  • Temperature range: -60 °C to 350 °C.

    Click here for more information on our Rxi® columns.

Syringe Filters with Luer-Lok® Inlet

Forensic Drug Screen Mixes

2.0 mL Autosampler Vial Convenience Kits

  • Vials packaged in a clear-lid tray. Preassembled caps with septa packaged separately in a plastic bag.
  • Black polypropylene open-hole caps and 8 mm red PTFE/silicone septa, 0.065″.

    For an instrument reference chart for 2.0 mL, 8 mm Screw-Thread Vials, click here.

Survival Kits for HPLC

  • Contain a wide range of tubing, fittings, and tools necessary to set up and maintain your HPLC system.
  • Available in stainless steel or PEEK™.
Chromablography
Blog

The Dynamic Duo is Here: Introducing a New Blood Alcohol Column Set!

Posted Tue, Dec 13, 2011 by Amanda Rigdon

*Cue theme music* Although I generally don’t highlight specific products in the blogs I write, I’m going to break my pattern to introduce the new blood alcohol (BAC) column set. Over the past several months, I’ve had the great luck to be able to work closely with our team of polymer chemists and engineers throughout [...]

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LC/MS in Forensic Toxicology: Selecting a Killer LC Column

An overview of the principles of LC/MS, focusing on the impact of column selection. Attendees will learn how to optimize separations using stationary phase selectivity and column dimensions.

Narrated by Becky Wittrig, Global HPLC Specialist, & Amanda Rigdon, Clinical/Forensics Applications Chemist. Length: 62 minutes

Sample Preparation of Cannabinoids in Urine Using the QuEChERS Method and dSPE Cleanup

This webinar introduces QuEChERS and dSPE and discusses their application to sample prep for GC/MS analysis of cannabinoids in urine. Attendees will learn how to increase sample throughput with this simple approach.

Narrated by Amanda Rigdon, Pharmaceutical Innovations Chemist.

Technical Articles

Clinical, Forensic & Toxicology

LC/MS/MS Analysis of Metabolites of Synthetic Cannabinoids JWH-018 and JWH-073 in Urine

This application note details a fast extraction and analysis method for a wide range of metabolites of synthetic cannabinoids JWH-018 and JWH-073 in urine. Quantitative results are reported for carboxylated and mono-hydroxylated metabolites, including positional isomers.

Clinical, Forensic & Toxicology

4.5 Minute Analysis of Benzodiazepines in Urine and Whole Blood Using LC/MS/MS and an Ultra Biphenyl Column

Sample throughput for benzodiazepines in urine and whole blood can be increased by adopting this dilute-and-shoot LC/MS/MS method which uses an Ultra Biphenyl HPLC column. Partial validation data are presented in this application note.

Clinical, Forensic & Toxicology

Reduce Downtime and Cost of Materials with Rugged Rxi®-5Sil MS GC Columns

New Rxi®-5Sil MS columns produce consistent results for amphetamine—even after 400 injections of derivatizing reagent—resulting in less time and money spent on column maintenance and replacement.

Clinical, Forensic & Toxicology

5 Minute Analysis of Vitamin D in Serum by LC/MS/MS

Conventional techniques for vitamin D analysis often lack adequate sensitivity, specificity, and speed. This LC/MS/MS assay results in highly symmetric peaks that elute in just 5 minutes.

PDF Document

Rxi®-5Sil MS: Assured Performance for Forensic Applications

Rxi®-5Sil MS columns produce excellent results for a number of forensic applications. The versatile selectivity separates a wide variety of compounds, which lets you keep analyzing samples instead of changing columns between methods. (PDF - 625kB)

PDF Document

Simplify Sample Prep and Protect Analytical Equipment With Syringe Filters

Filtering sample extracts with syringe filters will greatly extend the life of costly chromatographic columns and replacement parts, particularly for HPLC systems. This 2-page fact sheet includes helpful membrane, porosity, and size selection guides. (PDF - 119kB)

PDF Document

Biphenyl: Leading Resolution in LC for Clinical and Forensic Applications

Versatile Biphenyl columns provide excellent retention of both polar and nonpolar compounds, resulting in improved resolution of benzodiazepines, cannabinoids, and other key target compounds for clinical or forensic applications. (PDF - 633kB)

PDF Document

Fast, Definitive Data for Blood Alcohol Testing

New Rtx®-BAC Plus 1 and Rtx®-BAC Plus 2 columns provide definitive results quickly, so you can maximize sample throughput. These columns baseline separate all critical blood alcohol compounds, including ethanol, methanol, acetone, tert-butanol, acetaldehyde, isopropanol, and n-propanol, in less than 2 minutes. (PDF - 522kB)

PDF Document

New Rtx®-BAC Plus 1 and Rtx®-BAC Plus 2 Columns: Advanced Technology for Fast, Reliable Measurement of Alcohol in Blood

New Rtx®-BAC Plus columns outperform other blood alcohol column pairs and ensure baseline separation of all critical compounds. These columns provide definitive data in a fast, 2-minute analysis, so you can be certain of your results and maximize sample throughput. (PDF - 940kB)

PDF Document

Biphenyl: Next Generation of Phenyl Columns

Biphenyl columns provide both high hydrophobic retention and aromatic selectivity in the same column. Orthogonal separations can be achieved with simple mobile phase changes, giving markedly better separations for a wide variety of molecules. (PDF - 531kB)