How to Diagnose GC Septum Bleed Contamination Sources: Could it be Your Vial Cap?

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/General-Interest/general_GNAR2846-UNV

Abstract: In gas chromatography, septum bleed is often attributed to the inlet septum, but the vial cap septum can also be a source. Fortunately, it’s easy to determine which septum is causing the problem and by identifying it so you can avoid the time and trouble of unnecessary inlet maintenance. Read on to learn how to identify vial cap septum bleed and also how to choose a GC septum that will reduce the problem.

Upgrade to a Faster D2887 Analysis with a GC Accelerator Kit and Reduce Analysis Time to 9 Minutes in a 120 V GC

Author: Katarina Oden

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Petroleum-Petrochemical/petro_PCAN2900-UNV

Abstract: The results of a simulated distillation analysis are vitally important to the operation of refineries globally. For the analysis of petroleum samples within the boiling point range from 55.5 ˚C to 538 ˚C, ASTM D2887 is a standard method that has been accepted and is used industry-wide. This application note will demonstrate how a creative use of the Restek GC Accelerator oven insert kit can permit analysts using Agilent 6890/7890 GCs with 100/120 V ovens to successfully migrate from D2887’s slower Procedure A conditions to the accelerated Procedure B conditions without new instrumentation or software, resulting in a 9-minute analysis time that meets all method requirements.

LC Column Technology: The State of the Art

Authors: Gert Desmet1, Fabrice Gritti2, Xiaoli Wang3, Frank Steiner4, Dave Bell5, Tivadar Farkas6, Mel Euerby7

  1. Vrije Universiteit Brussel, 2. Waters Corporation, 3. Agilent Technologies, 4. Thermo Fisher Scientific, 5. Restek Corporation, 6. Phenomenex, Inc., 7. Shimadzu

Published By: LCGC Europe

Year of Publication: November 2017

Volume, Issue: Volume 30, Issue 11

Link: http://www.chromatographyonline.com/lc-column-technology-state-art 

Abstract: Key opinion leaders in the field discuss the current state of the art in liquid chromatography column technology in an extended special feature celebrating the 30th anniversary edition of LCGC Europe.

When Do We Need Sub-2-µm Superficially Porous Particles for Liquid Chromatography Separations?

Authors: David S. Bell, Landon Wiest, Shun-Hsin Liang, Dan Li

Restek Corporation

Published By: LCGC North America

Year of Publication: July 2018

Volume, Issue: Volume 36, Issue 7

Link: http://www.chromatographyonline.com/when-do-we-need-sub-2-m-superficially-porous-particles-liquid-chromatography-separations-0

Abstract: The use of superficially porous particles (SPPs) for modern high performance liquid chromatography (HPLC) is now very common. Initially, SPPs rose as an alternative to sub-2-µm fully porous particles (FPPs). In recent years, many column manufacturers have developed 2-µm and smaller SPP-based products. This article investigates the practical utility of these smaller SPP designs.

The Promise of Metal–Organic Frameworks for Use in Liquid Chromatography

Author: David S. Bell

Restek Corporation

Published By: LCGC North America

Year of Publication: June 2018

Volume, Issue: Volume 36, Issue 6

Link: http://www.chromatographyonline.com/promise-metal-organic-frameworks-use-liquid-chromatography

Abstract:  Metal–organic frameworks (MOFs) are self-assembled combinations of metals and inorganic ligands that result in a relatively young class of highly ordered, porous materials. Because of the number of structural and chemical possibilities, high surface area, controlled pore volume, and thermal properties, MOFs are being applied in a number of fields, including chromatography. Although there has been limited application of MOFs for liquid chromatography (LC), early studies have revealed great promise. In this installment of “Column Watch,” recent investigations toward the application of MOFs specifically for LC are presented and discussed.

Liquid Chromatography’s Complementary Role to Gas Chromatography in Cannabis Testing

Authors: Justin Steimling, Ty Kahler

Restek Corporation

Published By: Supplement to LCGC North America

Year of Publication:  June 2018

Volume, Number: Volume 36, Number s6

Link: http://files.pharmtech.com/alfresco_images/pharma/2018/06/13/f119cb54-ce43-4628-95f8-af1aa07bb6ff/LCGC_NAmerica_June2018Supp.pdf

Abstract: The absence of consensus methods for cannabis testing is a challenging, but refreshing opportunity for analytical chemists in the field because it enables the incorporation of the newest technologies and best practices without the restrictions imposed by legacy approaches that often impede method development in other industries. Liquid chromatography (LC) is proving to be a valuable complementary technique to gas chromatography (GC) in cannabis testing for the analysis of cannabinoids, mycotoxins, and pesticides. The industry is emerging during a time when superficially porous particles (SPPs) and ultrahigh-pressure liquid chromatography (UHPLC) have become market standards. This article discusses the adoption of LC technology and its role in cannabis testing.

Beyond Particle Technology

Author: David S. Bell

Restek Corporation

Published By: Supplement to LCGC North America

Year of Publication: June 2018

Volume, Number: Volume 36, Number s6

Link: http://files.pharmtech.com/alfresco_images/pharma/2018/06/13/f119cb54-ce43-4628-95f8-af1aa07bb6ff/LCGC_NAmerica_June2018Supp.pdf

Abstract: Two of the more significant technologies, sub-2-μm particles and superficially porous particles (SPP), have taken a firm hold on modern liquid chromatography practice. Each of these developments were initially met with both excitement and their share of skepticism. Both emotions drove extensive research and ultimately adoption of the ideas. Today, both technologies are routinely used in many industries around the world, but where do we go from here? This supplement was assembled to provide examples of the ongoing research that is building upon recent particle technology developments.

Reference Module in Chemistry, Molecular Sciences and Chemical Engineering: QuEChERS

Authors: Alexandria M. Pavkovich, David S. Bell

Restek Corporation

Published By: ScienceDirect

Year of Publication:  June 2018

Link: https://www.sciencedirect.com/science/article/pii/B9780124095472139721#!

Abstract: QuEChERS has become a widely accepted and highly adaptable method for pesticide residue analysis. The analytical scope and applicability of QuEChERS are expanding at a rapid pace. Numerous research groups work with QuEChERS for analysis of pesticides, veterinary drugs, mycotoxins, environmental and natural contaminants, drugs of abuse, and a number of other areas of interest.

The term QuEChERS is an acronym for Quick, Easy, Cheap, Effective, Rugged, and Safe. QuEChERS is a quick and relatively easy extraction method that uses low solvent volumes and a user-friendly collection vessel while providing acceptable and reproducible analyte recovery for a wide range of pesticides and target analytes. QuEChERS allows for the extraction of homogenized matrices by using salt formulations to drive the separation of the organic extraction solvent and water.

Faster Detailed Hydrocarbon Analysis (DHA) Using Hydrogen

Author: Barry Burger and Jan Pijpelink

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Petroleum-Petrochemical/petro_PCAR2891-UNV

Abstract: Robust Rtx-DHA columns are highly stable and can be run with hydrogen carrier gas under accelerated conditions. The hydrogen-based method for detailed hydrocarbon analysis shown here is twice as fast as traditional approaches, which allows labs to process samples faster and make more profitable decisions during product blending.

Analysis of FAMEs in Biodiesel Fuel: Pro EZGC Modeling Software Ensures Proper Column Selection

Author: Katarina Oden

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Petroleum-Petrochemical/petro_PCAN2889-UNV

Abstract: Polar columns were evaluated for the analysis of fatty acids methyl esters (FAMEs) in finished B100 biodiesel according to method EN 14103 (2011). Using Restek’s Pro EZGC chromatogram modeler, a high cyano phase Rt-2330 column and a polyethylene glycol phase FAMEWAX column were compared. The modeling software predicted an unacceptable coelution between the internal standard (C19:0 FAME) and FAME C18:2 when using the Rt-2330 column. However, the modeler also predicted that the FAMEWAX column would separate all the compounds of interest, which was demonstrated empirically. In addition, the results on the FAMEWAX column showed excellent repeatability for both total FAMEs and the linolenic acid methyl ester component.