Trace-Level Analysis of Melamine and Related Compounds by LC-MS/MS

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFSS2792-UNV

Abstract: The analysis of melamine and related compounds is critical in protecting consumers from adulterated food products. While these highly polar analytes are difficult to retain and accurately quantify on many columns, the Raptor HILIC-Si column and LC-MS/MS method shown here allow quick and complete separations, so melamine and related compounds can be accurately identified and quantified even at residual levels.

LC-MS/MS Analysis of Paraquat and Diquat without Ion-Pairing Reagents

Published By: Restek Corporation

Year of Publication: 2017

Link:http://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVSS2791-UNV

Abstract: LC-MS/MS analysis of paraquat and diquat herbicides is an important tool for protecting human and environmental health. However, the ion pairing reagents that are commonly used to improve retention, resolution, and peak shape have a negative impact on sensitivity and can contaminate the system necessitating frequent cleaning. The LC-MS/MS analysis of paraquat and diquat presented here provides complete separation and good peak response for both target analytes in a fast, 7-minute gradient run without the use of troublesome ion pairing reagents.

Highly Selective LC-MS/MS Analysis of Mycotoxins from Multiple Classes

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFSS2790-UNV

Abstract: Mycotoxin contamination of crops is not only a public health concern, but it also has a huge impact on the global economy. This highly selective LC-MS/MS analysis of 20 mycotoxins in just 9 minutes allows scientists to accurately identify toxins, to monitor food products for contamination, and to support control strategies that prevent economic loss.

 

Fast, Accurate LC-MS/MS Method for Folate Deficiency Biomarkers in Plasma

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFSS2789-UNV

Abstract:

LC-MS/MS methods for folate deficiency biomarkers in plasma are complicated by the presence of matrix phospholipids and lysophospholipids. These interferences are problematic with reversed-phase LC because they can suppress response, reduce accuracy, and contaminate the MS source. Using a Raptor HILIC-Si column and the HILIC method shown here, folate deficiency biomarkers are completely separated from matrix interferences, allowing accurate determinations to be made in a fast, 5-minute analysis.

Definitive EtG/EtS LC-MS/MS Analysis: A Rugged 4-Min Method for High-Throughput Labs

Author: Justin Steimling and Frances Carroll

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFAN2736-UNV

Abstract:

Methods for monitoring alcohol consumption biomarkers EtG and EtS are generally limited by poor retention and coelution with matrix interferences, as well as by long analysis times and short column lifetimes. The dilute-and-shoot EtG/EtS LC-MS/MS analysis developed here using the novel Raptor EtG/EtS column easily resolves EtG and EtS from matrix interferences, providing consistent, accurate results for high-throughput labs testing human urine samples for alcohol consumption.

Column Conditioning Ensures Consistent EtG/EtS Results

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFAR2737-UNV

Abstract:

By properly conditioning new columns and employing Restek’s EtG/EtS method for sample prep and analysis, high-throughput labs testing human urine samples for these alcohol consumption biomarkers can ensure accurate, consistent results with fewer column changes.

Meeting NJ Low Level TO-15 Air Testing Method Requirements

Author: Jason Herrington

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/Air-Sampling/env_EVAN2708-UNV

Abstract:

The NJ low level TO-15 air testing method is based on U.S. EPA Method TO-15, but it has more some differences that make it quite challenging. The broader calibration range (0.2–40 ppbv) is particularly difficult to meet. In this application note, we focus on the method’s analytical requirements and demonstrate how to meet them using a Markes Unity with CIA Advantage and a 30 m Rtx-VMS column.

Will Pro EZGC Chromatography Modeling Software Work For You? We Put It to the Test!

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/General-Interest/general_GNAR2714-UNV

Abstract:

When it comes to speeding up method development, Pro EZGC modeling software saves you time, materials, and a lot of frustration. This technical article puts Restek’s GC chromatogram simulator to the test and demonstrates how well it predicts actual experimental outcomes.

Instrumentation for Heavy Metals Analysis in Cannabis

Author: Chris English

Restek Corporation

Published By: Cannabis Industry Journal

Year of Publication: 2017

Link: https://www.cannabisindustryjournal.com/column/instrumentation-for-heavy-metals-analysis-in-cannabis/

Abstract:

Heavy metals are common environmental contaminants often resulting from mining operations, industrial waste, automotive emissions, coal fired power plants, amount other sources. Flame Atomic Absorption Spectroscopy (Flame AA) and Graphite Furnace Atomic Absorption Spectroscopy (GFAA) are both techniques that determine both the identity and quantity of specific elements.

Instrumentation Used for Terpene Analysis

Author: Tim Herring

Restek Corporation

Published By: Cannabis Industry Journal

Year of Publication: 2017

Link: https://www.cannabisindustryjournal.com/column/instrumentation-used-for-terpene-analysis/

Abstract:

Because terpenes are somewhat volatile, the Restek team recommends using gas chromatography and advises against using HPLC for terpene analysis.

Many customers ask technical service which instrumentation is best, GC or HPLC, for analysis of terpenes. Terpenes are most amenable to GC, due to their inherent volatility. HPLC is generally not recommended; since terpenes have very low UV or MS sensitivity; the cannabinoids (which are present in percent levels) will often interfere or coelute with many of the terpenes.