Author(s): Jaap de Zeeuw
Published By: Separation Science
Issue: vol. 5, issue 10
Year of Publication: 2013
For the full print issue, visit http://www.sepscience.com/docs/Bespoke/Editions/SepSci/Sepsci1013eu.pdf?utm_source=iContact&utm_medium=email&utm_campaign=eLearning%20Newsletter%20-%20Europe%20Sep%20Sci&utm_content=
Abstract: In the last issues we discussed possible sources for ghost peaks related to the carrier gas, gas lines, injection port and parts, degradation, and the column. Here we move onto several other contributions that are not as obvious as the former options.
Restek is excited to announce the evolution of superficially porous particles with the introduction of Raptor™ LC columns.
Superficially porous particles (commonly referred to as SPP or “core-shell” particles) changed the world of LC by dramatically boosting column efficiency and reducing analysis times, but they were only the beginning. With Raptor™ LC columns, Restek chemists have combined the speed of SPP with the resolution of highly selective USLC® technology. This new species of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. Raptor™ LC columns provide the practicing analyst with the most powerful tools available for fast, efficient method development and increased sample throughput. And because they are from Restek, Raptor™ LC columns are backed by manufacturing and quality systems you trust along with internationally renowned Plus 1 service.
The first phase to be rolled out is the innovative Biphenyl, which will be followed by a full suite of selective USLC® phases. The industry-leading Biphenyl is Restek’s most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries. As a result, the rugged Raptor™ Biphenyl column is extremely useful for fast separations in bioanalytical testing applications like drug and metabolite analyses, especially those that require a mass spectrometer (MS). Increasing retention of early-eluting compounds can limit ionization suppression, and the heightened selectivity also helps eliminate the need for complex mobile phases that are not well suited for MS detection. Restek was the first to bring chemists the benefits of the Biphenyl ligand and has the knowledge to maximize SPP performance of this premier phenyl chemistry.
To help further extend the life of already-rugged Raptor™ LC columns, Restek has also mated these new superficially porous particles with patent-pending guard column hardware developed by Optimize Technologies. Sold separately and available in three different IDs, the Raptor™ LC guard column cartridge in an EXP® direct connect holder is the ultimate in column protection. Change cartridges without breaking inlet/outlet fluid connections—and without tools.
Experience Selectivity Accelerated. Put Raptor™ LC columns and guards to the test today on your most challenging workflows!
Ethylene oxide and 1,4-dioxane are considered probable carcinogens by the U.S. EPA and International Agency for Research on Cancer respectively. These compounds are impurities in polyethylene glycol (PEG), but because of the potential danger they pose to humans, they must be removed before PEG can be used as a thickener / softener in cosmetics and personal care products.
Restek has formulated the only off-the-shelf suite of reference standards targeted toward the analysis of PEG-based products to make it easier for labs to verify the safety of shampoos, hand creams, and more. Produced with the specific concentrations needed in the industry, these newest Restek® certified reference materials (CRMs) are quantitatively tested to confirm their composition, and detailed support documentation is provided with each purchase. Because they are manufactured and QC-tested in Restek’s ISO-accredited labs, they also help satisfy ISO requirements.
With the release of these new ready-made reference standards, contract labs and manufacturers of PEG-based cosmetics and personal care products no longer need to order custom standards or make their own mixes.