Improve Your Environmental Chromatography with Shimadzu & Restek

Environmental Chromatography SymposiumRestek Business Development Manager Joe Konschnik will be presenting at an upcoming Shimadzu environmental symposium:

Environmental Methods… Past, Present & Future
Where it all started, enhancements for today, and method updates toward tomorrow

Taking place on November 6, 2015, at Shimadzu’s state-of-the-art facility in Columbia, MD, this meeting will give you a chance to learn from some of the industry’s renowned experts. Joe’s presentation will focus on improving your results with either LC or GC:

Peaks and Valleys: Good Chromatography and How to Keep It That Way
Presenter: Joe Konschnik

Getting the most out of your instrument is what every environmental lab wants. In utilizing recent technology innovations for both LC and GC, environmental chemists will achieve faster run times, increase sample throughput, and minimize instrument downtime. Fast LC is now possible with either conventional or ultra-high pressure HPLCs. Shoot-&-dilute GC techniques offer both instrument performance and data quality enhancements. Both are available and enable your lab to gain the productivity it needs to keep up with today’s testing lab demands.

And speakers from other manufacturers and agencies will cover a variety of topics of concern for environmental labs. The day’s featured speaker will be retired U.S. EPA Office of Water Director Bill Telliard, who will recount his years with the EPA and explore the history of the Clean Water Act as well as the future of EPA methods for drinking water, wastewater, and solid waste. The symposium will conclude with a roundtable discussion.

This event is open to anyone interested in improving their results and accelerating their analyses. Breakfast, lunch, and refreshments will be provided. And, raffles will be held throughout the day with a variety of great prizes!

Register today at http://events.r20.constantcontact.com/register/event?oeidk=a07ebn503oedf66f896&llr=lkmvzwpab

Jaap de Zeeuw to Give Plenary Address at 22nd Norwegian Symposium on Chromatography

Jaap de Zeeuw

Jaap de Zeeuw

Restek’s Jaap de Zeeuw will be presenting an invited keynote lecture during the plenary session at the 22nd Norwegian Symposium on Chromatography. This focused technical conference will be held January 12, 2016 in Sandefjord, Norway, and is well known for its high-quality technical presentations and enjoyable social program. Jaap’s talk will focus on converting from helium carrier gas to nitrogen carrier gas while maintaining exactly the same separation efficiency, retention times, and peak elution order without changing the oven temperature conditions. The potential of nitrogen carrier gas is often overlooked because it has low optimal flow and velocity. However, Jaap’s work shows that by using proper method translation and a shorter, narrower column it is possible to obtain the same separation while benefiting from the lower cost and consistent availability of nitrogen carrier gas.

 

Attend Restek’s Vendor Seminar on GC-MS/MS Performance at RAFA 2015

In addition to exhibiting, Restek will hold a vendor seminar at the 7th International Symposium on Recent Advances in Food Analysis (RAFA). Presented by Restek’s own Julie Kowalski on November 5 at 1:30 p.m., this valuable seminar will explore prolonging GC-MS/MS performance by means of Shoot-and-Dilute injection versus analyte protectants. Prizes will also be given away to select attendees.

RAFA 2015 takes place on November 3–6, 2015 at the Clarion Congress Hotel Prague, Czech Republic. This biennial symposium summarizes the latest strategies and identifies current issues surrounding food quality and safety control analysis and bioanalysis. While at RAFA, be sure to also stop by Booth# 46 for a visit and to discuss our latest innovations in food science.

Visit http://www.rafa2015.eu/programme_vendors_seminars.html today to register for the symposium and to sign up for Restek’s vendor seminar.

Prolonging GC-MS/MS Performance: Shoot-and-Dilute Injection versus Analyte Protectants

Thursday, November 5, 1:30 p.m.
Julie Kowalski and Jack Cochran
Restek Corporation

For more information, e-mail  julie.kowalski@restek.com

In gas chromatography–mass spectrometry (GC-MS), most problems occur on the front end, at the GC inlet, where compounds can degrade during hot splitless injection, active compounds can be irreversibly adsorbed to inlet liner surfaces, and nonvolatile material from dirty samples can compromise the transfer of less volatile compounds of interest from the inlet to the GC column. These issues are magnified due to the very slow inlet flow during splitless injection, which is typically less than 2 mL/min.

Two strategies to mitigate these issues will be demonstrated in this seminar. One approach is to use split injection, what we call, and “Shoot-and-Dilute.” With newer, more sensitive GC-MS/MS systems, LOD and LOQ requirements are often achievable using split injections at ratios of 10:1 or greater. Increased flow through the inlet during split injection minimizes residence time inside the inlet liner, which decreases compound degradation and adsorption, and maintains acceptable data quality longer. In addition, GC oven start temperature can be higher, thus reducing overall run time as well as the time needed to re-equilibrate the GC oven prior to the next analysis. Another benefit of split injection is improved peak shape for early eluting pesticides when injecting acetonitrile-based QuEChERS extracts.

The second strategy to overcome GC inlet problems is to use “analyte protectants,” which are essentially volatile and chromatograph-able masking agents such as sugars, diols, etc., that are co-injected with each sample and standard to temporarily occupy active sites in the GC inlet liner and column. These analyte protectants have low m/z ions and the mass spectrometer can essentially overlook them in favor of target compounds.

Both strategies were tested with multiclass pesticides and compared against a typical splitless injection method without use of analyte protectants for QuEChERS samples. For Shoot-and-Dilute, viability of split injection based on detectability of a wide range of analytes was determined. Optimized split injection, inlet, and initial GC oven temperatures were determined. Benefits of analyte protectants were evaluated by peak shapes and responses of both well-behaved and problem pesticides. The goal of both Shoot-and-Dilute and analyte protectants approaches is to improve initial and long-term chromatographic performance.

Determination of Emerging Contaminants in Wastewater Utilizing Comprehensive Two-Dimensional Gas-Chromatography Coupled with Time-of-Flight Mass Spectrometry

Author(s): Sarah Prebihalo1, Adrienne Brockman1, Jack Cochran1,2, Frank L. Dorman1,3

1. Pennsylvania State University, Forensic Science Program
2. Restek Corporation
3. Pennsylvania State University, Department of Biochemistry and Molecular Biology

Published By: Journal of Chromatography A

Year of Publication: 2015

Link: www.sciencedirect.com/science/article/pii/S0021967315014132

Abstract: An analytical method for identification of emerging contaminants of concern, such as pesticides and organohalogens has been developed and utilized for true discovery-based analysis. In order to achieve the level of sensitivity and selectivity necessary for detecting compounds in complex samples, comprehensive gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOFMS) was utilized to analyze wastewater samples obtained from the Pennsylvania State University wastewater treatment facility (WWTF). Determination of emerging contaminants through a process of combining samples which represent “normal background” and comparing this to new samples was developed. Results show the presence of halogenated benzotriazoles in wastewater samples as well as soil samples from Pennsylvania State University agricultural fields. The trace levels of chlorinated benzotriazoles observed in the monitoring wells present on the property indicate likely environmental degradation of the chlorinated benzotriazoles. Preliminary investigation of environmental fate of the substituted benzotriazoles indicates their likely degradation into phenol; an Environmental Protection Agency (USEPA) priority pollutant.

Aura™ Personal Air Samplers—a New Approach for Industrial Hygiene

Aura press releaseThe Aura™ personal air sampler from Restek is setting a new standard in sampling technology. This innovative passive sampling device is designed to meet OSHA and NIOSH requirements, while overcoming the limitations of sorbent tubes and badges. Notably, this quiet, robust sampler does not require a pump and manages variations in face velocity, temperature, and humidity better than traditional sampling approaches. Since this is a whole air sampling technique, it allows multiple analyses of >100 VOCs, providing broader application utility than analyte-specific sorbent techniques. The Aura™ personal air sampler has a wider effective range than tubes and badges—it is sensitive down to pptv levels and there is no risk of breakthrough even at ppmv levels. Comfortable to wear and easy to operate, this novel sampler features a simple, quick connection that starts and stops flow with no flow calibration required.

Learn more at www.restek.com/Aura

Changing from Helium and Nitrogen While Maintaining Separation Efficiency and Analysis Time

Author(s): Jaap de Zeeuw and Jack Cochran
Restek Corporation

Published By: LCGC’s The Column

Year of Publication: 2015

Link: http://images2.advanstar.com/PixelMags/lctc/digitaledition/October26-2015-us.html#2

Abstract: Most scientists in the world of gas chromatography (GC) will advise you not to use nitrogen because it is considered a “dinosaur” gas and, instead, use helium, which offers shorter analysis time. But, wouldn’t it be very nice if we could make nitrogen work for applications where helium is not an option?