LC-MS/MS Analysis of Paraquat and Diquat without Ion-Pairing Reagents

Published By: Restek Corporation

Year of Publication: 2017

Link:http://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVSS2791-UNV

Abstract: LC-MS/MS analysis of paraquat and diquat herbicides is an important tool for protecting human and environmental health. However, the ion pairing reagents that are commonly used to improve retention, resolution, and peak shape have a negative impact on sensitivity and can contaminate the system necessitating frequent cleaning. The LC-MS/MS analysis of paraquat and diquat presented here provides complete separation and good peak response for both target analytes in a fast, 7-minute gradient run without the use of troublesome ion pairing reagents.