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Pinnacle^® DB HPLC & UHPLC Columns

Base deactivated silica—ideal for analysis of basic compounds or bases mixed with acids/neutrals.
Available phases: Biphenyl, C8, Cyano, Silica, Phenyl, PFP Propyl, PAH, IBD, C18, Aqueous C18.
1.9 µm columns for UHPLC and 3 or 5 µm columns for standard HPLC.

Rxi^® Capillary GC Columns

The ultimate high performance fused silica capillary column.

Certified Autosampler Vial Kits

Certified Vials, 2.0 mL Screw-Thread Vials

Certificates enclosed with each kit.
Vials of clear or amber borosilicate glass, with ID marking spots.
Closures with pre-inserted septa.
Each kit sealed for integrity.

Syringe Filters with Luer-Lok^® Inlet

Luer-Lok® inlet offers leak-tight syringe connection.
Variety of filter types, porosities, and diameters.
Color coded for easy identification.
Rugged polypropylene housing.
Autoclavable to 121 °C for 15 minutes.
Quantity break pricing for greater savings.

Simplify Sample Prep and Protect Analytical Equipment Using Syringe Filters (119k PDF)

Looking for Syringes?
Restek offers the inert, non-reactive NORM-JECT® Polypropylene Syringes.

Syringe filters are for laboratory use only.

USP Residual Solvent Standards

USP equivalent standards for the revised USP <467> general chapter—compliance without the cost—compare prices today.
The only complete source for USP <467>.

LC/MS and GC/MS Analysis of Potential Genotoxic Impurities in Active Pharmaceutical Ingredients

Guidelines have recently been established for levels of potential genotoxic impurities (PGIs) in pharmaceutical APIs. This webinar outlines LC/MS and GC/MS methods developed in collaboration with Merck & Co.

Narrated by Amanda Rigdon, Innovations Chemist. Length: 17 minutes

The Analysis of Residual Solvents—Implementing USP <467>

Chromatographers implementing USP <467> Residual Solvents will benefit from this webinar which discusses system optimization and implementation strategies for USP <467>, as well as headspace GC fundamentals.

Narrated by Rick Lake, Pharmaceutical Market Development Manager.

Using Phenyl Column Chemistry to Optimize Reversed Phase Separations

Narrated by Rick Lake, Pharmaceutical Market Development Manager.

Troubleshooting the Acetonitrile Shortage—Strategies for Today and Tomorrow

Narrated by Rick Lake, Pharmaceutical Market Development Manager.

USLC™ Columns Put the Right Tools in Your LC Method Development Toolbox Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection

Column selectivity has the most significant influence on chromatographic peak separation, or resolution, so choosing the right column can greatly speed up HPLC and UHPLC method development. In this article, we discuss column choice and identify a set of just 4 stationary phases—Restek’s USLC™ column set—that encompasses the widest range of reversed phase selectivity available today.

Two Options for Analyzing Potential Genotoxic Impurities in Active Pharmaceutical Ingredients

Two options for the analysis of PGIs in API have been developed by Merck and Restek to meet different laboratory needs. The first option is a fast method for the analysis of sulfonate esters on the Rxi^®-5Sil MS column. The second option is a comprehensive method for the analysis of both sulfonate esters and alkyl halides on the Rtx^®-200 column. Both methods require very little sample preparation, which helps increase laboratory productivity.

Pesticides in Dietary Supplements: Advantages of QuEChERS vs. PAM 303

Restek has developed the first QuEChERS-based method for determining pesticide residues in dietary supplements. This simple, cost-effective procedure reduces matrix interferences as well as sample prep variation among technicians.

Explaining the Small Particle Advantage Faster Sample Throughput on a 1.9µm Pinnacle™ DB Column

Small particle HPLC columns can offer faster analysis times but only if the particle size distribution is tightly controlled. Restek’s 1.9µm Pinnacle™ DB columns have tight, symmetric particle size distributions and contain no particles less than 1µm. Here we demonstrate how our stringent quality requirements translate into faster, more reproducible results compared to competitor columns. Greater column efficiency and reproducibility mean faster throughput and more consistent results.

Determining Pesticides in Dietary Supplements with QuEChERS Extraction, Cartridge SPE, and GCxGC-TOFMS

The novel approach used here combines QuEChERS extraction, cartridge SPE cleanup, and GCxGC-TOFMS analysis, resulting in good recoveries for a wide range of pesticides in dietary supplements. Matrices include dandelion root, sage, and a multi-herb finished product. (PDF - 394kB)

Simplify Sample Prep and Protect Analytical Equipment With Syringe Filters

Filtering sample extracts with syringe filters will greatly extend the life of costly chromatographic columns and replacement parts, particularly for HPLC systems. This 2-page fact sheet includes helpful membrane, porosity, and size selection guides. (PDF - 119kB)

USLC™ Columns: Choose Columns Fast. Develop Methods Faster.

Restek USLC™ columns offer the widest range of selectivity available and are an integral part of successful method development. Ideal for column switching systems, these columns provide orthogonal separations to create optimal resolution and robust methods—all in a 4-column set. (PDF - 1813kB)

USLC™ Column Selection & Mobile Phase Adjustment Guide

USLC™ columns and this guide will help you easily choose the right stationary phase to target nearly any analyte in reversed phase or HILIC method development. It will also help you adjust your mobile phase to further improve results without guesswork or wasted time. (PDF - 1682kB)

Custom Residual Solvents Mixes

Save time and money—let Restek custom blend reference standards specifically for your residual solvent testing needs! (PDF - 76kB)

Biphenyl: Next Generation of Phenyl Columns

Biphenyl columns provide both high hydrophobic retention and aromatic selectivity in the same column. Orthogonal separations can be achieved with simple mobile phase changes, giving markedly better separations for a wide variety of molecules. (PDF - 531kB)

Residual Solvent Analysis: Implementing USP <467>

This 12-page reference includes a review of headspace fundamentals, the revised USP <467> method (July, 2008), chromatography for Procedures A, B, and C, and technical tips for optimization. Guidance on fast, effect method development is given. (PDF - 471kB)

Rxi^®-624Sil MS

Develop impurity methods faster and more efficiently using a single column that combines the selectivity of a 624 with the thermal stability of a 1 or 5 type column. The new Rxi^®-624Sil MS column offers good retention of polar compounds, mass spec compatibility, and unsurpassed inertness, making it the most broadly applicable GC column available to the pharmaceutical industry. (PDF - 1058kB)

Pharmaceutical Solutions

Certified Vials, 2.0 mL Screw-Thread Vials

for Agilent HPLC Systems

for Hitachi HPLC Systems

for Thermo HPLC Systems

for Waters Detectors

for Waters Detectors

Restek has developed the first QuEChERS-based method for determining pesticide residues in dietary supplements. This simple, cost-effective procedure reduces matrix interferences as well as sample prep variation among technicians.

The novel approach used here combines QuEChERS extraction, cartridge SPE cleanup, and GCxGC-TOFMS analysis, resulting in good recoveries for a wide range of pesticides in dietary supplements. Matrices include dandelion root, sage, and a multi-herb finished product. (PDF - 394kB)

Filtering sample extracts with syringe filters will greatly extend the life of costly chromatographic columns and replacement parts, particularly for HPLC systems. This 2-page fact sheet includes helpful membrane, porosity, and size selection guides. (PDF - 119kB)

Restek USLC™ columns offer the widest range of selectivity available and are an integral part of successful method development. Ideal for column switching systems, these columns provide orthogonal separations to create optimal resolution and robust methods—all in a 4-column set. (PDF - 1813kB)

USLC™ columns and this guide will help you easily choose the right stationary phase to target nearly any analyte in reversed phase or HILIC method development. It will also help you adjust your mobile phase to further improve results without guesswork or wasted time. (PDF - 1682kB)

Save time and money—let Restek custom blend reference standards specifically for your residual solvent testing needs! (PDF - 76kB)

Biphenyl columns provide both high hydrophobic retention and aromatic selectivity in the same column. Orthogonal separations can be achieved with simple mobile phase changes, giving markedly better separations for a wide variety of molecules. (PDF - 531kB)

This 12-page reference includes a review of headspace fundamentals, the revised USP <467> method (July, 2008), chromatography for Procedures A, B, and C, and technical tips for optimization. Guidance on fast, effect method development is given. (PDF - 471kB)

GC_PH01076

GC_PH1144

GC_PH1145

GC_PH00951