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Food, Flavor, and Fragrance Reference Standards <
Derivatization Reagents
Derivatization Reagents: Acylation Reagents
- Most commonly used for Electron Capture Detection.
- React with alcohols, amines and phenols.
- Frequently used for drugs of abuse confirmation.
Acylation reagents offer the same types of advantages available from silylation reagents: creating less polar, more volatile derivatives. In comparison to silylating reagents, the acylating reagents can more readily target highly polar multi-functional compounds, such as carbohydrates and amino acids. In addition, acylating reagents offer the distinct advantage of introducing electron-capturing groups, thus enhancing detectability during analysis.
