Mobile phase buffers are critical for HILIC methods because the ionization state of both the analytes and stationary phases will impact the separation. Here, we share an effective strategy for quickly optimizing buffer pH and concentration during method development.
Even the smallest gas leak can cause a loss in sensitivity, contaminate samples, damage columns and instruments, and lead to a lot of wasted time. Grab your leak detector and check these 10 common leak locations now to keep your GC running smoothly.
When preparing calibration standards, reducing sources of error is vital for accurate quantitative data. This article shares best practices relating to equipment, chemical interactions, and workflow solutions that will improve certainty in your analytical results.