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HPLC & UHPLC Columns

HPLC & UHPLC Analytical Columns

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Raptor ARC-18 LC Columns (USP L1) Ideal for high-throughput LC-MS/MS applications with minimal sample preparation. Well-balanced retention profile for better detection and integration of large, multiclass analyte lists. Sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality. Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica. View Product Information
Raptor C18 LC Columns (USP L1) A traditional end-capped C18 ideal for general-purpose use in reversed-phase chromatography. Wide pH range (2–8) provides excellent data quality for many applications, matrices, and compounds. Offers the highest hydrophobic retention of any Raptor phase. Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica. View Product Information
Raptor Biphenyl LC Columns (USP L11) Ideal for bioanalytical testing applications like drug and metabolite analyses. Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries. Limits ionization suppression and allows simple, MS-friendly mobile phases. Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica. View Product Information
Raptor FluoroPhenyl LC Columns (USP L43) Capable of both reversed-phase and HILIC separations. Ideal for increasing sensitivity and selectivity in LC-MS analyses. Offers increased retention for charged bases. Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica. Switch to a Raptor FluoroPhenyl LC column when you need more retention and selectivity for basic and hydrophilic compounds than you can achieve on a C18. View Product Information
Raptor HILIC-Si LC Columns (USP L3) HILIC silica column designed for increased retention of polar compounds without ion-pairing reagents. 2.7 µm Raptor core-shell particles provide the speed of SPP, with greater efficiency and capacity than 5 µm particles. Ideal for increasing sensitivity and selectivity in LC-MS analyses. Fully compatible with both HPLC and UHPLC when using low back-pressure HILIC mobile phases. Switch to a Raptor HILIC-Si LC column when you need more retention and resolution of hydrophilic, polar analytes. View Product Information
Force FluoroPhenyl LC Columns (USP L43) Capable of both reversed-phase and HILIC separations. Ideal for increasing sensitivity and selectivity in LC-MS analyses. Offers increased retention for charged bases. View Product Information
Force C18 LC Columns (USP L1) A traditional end-capped C18 ideal for general-purpose use in reversed-phase chromatography. Wide pH range (2–8) provides excellent data quality for many applications, matrices, and compounds. Offers high hydrophobic retention. View Product Information
Force Biphenyl LC Columns (USP L11) Ideal for bioanalytical testing applications like drug and metabolite analyses. Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries. Limits ionization suppression and allows simple, MS-friendly mobile phases. Restek’s most popular LC stationary phase. View Product Information
Ultra Biphenyl Columns (USP L11) Stationary Phase Category: phenyl (L11) Ligand Type: unique Biphenyl Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 15% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB Biphenyl Columns (USP L11) Stationary Phase Category: phenyl (L11) Ligand Type: unique Biphenyl Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: 8% End-Cap: yes Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
PFAS Delay Column Particle: 5 µm, spherical pH Range: 2.5 to 8 Maximum Temperature: 80 °C Maximum Pressure: 1,034 bar/15,000 psi View Product Information
Roc Silica HPLC Columns (USP L3) Conventional HPLC column built to be the cornerstone for your lab; pressure rated for any 400 bar HPLC system. Solid and reliable—delivers the peak shape, reproducibility, ruggedness, and performance you demand. Exceptional value for routine analyses and large-volume workflows—high-purity, fully porous silica backed by quality manufacturing features a variety of phases to fit most HPLC methods. Ideal for a wide range of applications from food to pharma; 5 phases cover 98% of USP methods. View Product Information
Roc Cyano HPLC Columns (USP L10) Conventional HPLC column built to be the cornerstone for your lab; pressure rated for any 400 bar HPLC system. Solid and reliable—delivers the peak shape, reproducibility, ruggedness, and performance you demand. Exceptional value for routine analyses and large-volume workflows—high-purity, fully porous silica backed by quality manufacturing features a variety of phases to fit most HPLC methods. Ideal for a wide range of applications from food to pharma; 5 phases cover 98% of USP methods. View Product Information
Roc Phenyl-Hexyl HPLC Columns (USP L11) Conventional HPLC column built to be the cornerstone for your lab; pressure rated for any 400 bar HPLC system. Solid and reliable—delivers the peak shape, reproducibility, ruggedness, and performance you demand. Exceptional value for routine analyses and large-volume workflows—high-purity, fully porous silica backed by quality manufacturing features a variety of phases to fit most HPLC methods. Ideal for a wide range of applications from food to pharma; 5 phases cover 98% of USP methods. View Product Information
Roc C18 HPLC Columns (USP L1) Conventional HPLC column built to be the cornerstone for your lab; pressure rated for any 400 bar HPLC system. Solid and reliable—delivers the peak shape, reproducibility, ruggedness, and performance you demand. Exceptional value for routine analyses and large-volume workflows—high-purity, fully porous silica backed by quality manufacturing features a variety of phases to fit most HPLC methods. Ideal for a wide range of applications from food to pharma; 5 phases cover 98% of USP methods. View Product Information
Roc C8 HPLC Columns (USP L7) Conventional HPLC column built to be the cornerstone for your lab; pressure rated for any 400 bar HPLC system. Solid and reliable—delivers the peak shape, reproducibility, ruggedness, and performance you demand. Exceptional value for routine analyses and large-volume workflows—high-purity, fully porous silica backed by quality manufacturing features a variety of phases to fit most HPLC methods. Ideal for a wide range of applications from food to pharma; 5 phases cover 98% of USP methods. View Product Information
Pinnacle DB IBD UHPLC Columns (USP L68) Stationary Phase Category: polar-embedded alkyl (L68) Ligand Type: proprietary polar functional embedded alkyl Particle: 1.9 µm, spherical Pore Size: 140 Å Carbon Load: proprietary End-Cap: no Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB PAH UHPLC Columns Particle: 1.9 µm, spherical Pore Size: 140 Å Carbon Load: proprietary End-Cap: no Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB PFP Propyl Columns (USP L43) Stationary Phase Category: fluorophenyl propyl (L43) Ligand Type: pentafluorophenyl propyl Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: 6% End-Cap: yes Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva Biphenyl Columns (USP L11) Stationary Phase Category: phenyl (L11) Ligand Type: Biphenyl Particle: 5 µm, spherical Pore Size: 300 Å Carbon Load: 7% End-Cap: yes Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva PFP Propyl Columns (USP L43) Stationary Phase Category: fluorophenyl propyl (L43) Ligand Type: pentafluorophenyl propyl Particle: 5 µm, spherical Pore Size: 300 Å Carbon Load: 5% End-Cap: yes Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva C4 Columns (USP L26) Stationary Phase Category: C4, butylsilane (L26) Ligand Type: monomeric C4 Particle: 5 µm, spherical Pore Size: 300 Å Carbon Load: 3.5% End-Cap: yes Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva C8 Columns (USP L7) Stationary Phase Category: C8, octylsilane (L7) Ligand Type: monomeric C8 Particle: 5 µm, spherical Pore Size: 300 Å Carbon Load: 5% End-Cap: yes Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva C18 Columns (USP L1) Stationary Phase Category: C18, octadecylsilane (L1) Ligand Type: monomeric C18 Particle: 3 µm or 5 µm, spherical Pore Size: 300 Å Carbon Load: 9% End-Cap: yes Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Viva Silica Columns (USP L3) Stationary Phase Category: bare silica (L3) Ligand Type: none Particle: 5 µm, spherical Pore Size: 300 Å Carbon Load: n/a End-Cap: n/a Surface Area: 100 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB Silica Columns (USP L3) Stationary Phase Category: bare silica (L3) Ligand Type: none Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: n/a End-Cap: n/a Surface Area: 150 m²/g pH Range: 2.5 to 8.0 Maximum Temperature: 80 °C View Product Information
Pinnacle DB Cyano Columns (USP L10) Stationary Phase Category: cyano (L10) Ligand Type: cyanopropylsilane Particle: 1.9 µm or 5 µm, spherical Pore Size: 140 Å Carbon Load: 4% End-Cap: yes Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB C8 Columns (USP L7) Stationary Phase Category: C8, octylsilane (L7) Ligand Type: monomeric C8 Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: 6% End-Cap: yes Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle DB C18 Columns (USP L1) Stationary Phase Category: C18, octadecylsilane (L1) Ligand Type: monomeric C18 Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: 11% End-Cap: yes Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Allure Silica Column for MOSH/MOAH Analysis Particle: 5 µm, spherical Pore Size: 60 Å Carbon Load: n/a End-cap: n/a Surface Area: 450 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C Highly retentive phase for normal phase separations. Very high surface area, Type B silica packing. Ideal for MOSH/MOAH analysis by EN 16995. For compatibility with Axel Semrau and other automated systems, add the Level 3 Trident column protection system and Allure Silica guard cartridge listed in Related Products. View Product Information
Raptor EtG/EtS LC Column Proven performance for accurate, reliable ethyl glucuronide (EtG) and ethyl sulfate (EtS) analysis. Strong retention consistently resolves analytes from matrix interferences. Long column lifetime ensures consistent performance injection after injection. Fast, 4-minute, dilute-and-shoot LC-MS/MS analysis supports high sample throughput. View Product Information
USLC Method Development Toolbox All the Right Tools—All in One Toolbox Ultra Selective Liquid Chromatography (USLC) method development toolbox contains all four USLC stationary phases in one convenient package. Available for UHPLC (1.9 μm) and HPLC (3 or 5 μm) in 50, 100, or 150 mm lengths. View Product Information
Ultra Aromax Columns (USP L11) Stationary Phase Category: phenyl (L11) Ligand Type: proprietary phenyl ligand Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 17% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra PFP Propyl Columns (USP L43) Stationary Phase Category: fluorophenyl propyl (L43) Ligand Type: pentafluorophenyl propyl Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 11% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Pinnacle II PAH HPLC Columns Particle: 4 µm, spherical Pore Size: 110 Å Carbon Load: proprietary End-Cap: no Surface Area: 180 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Allure AK Columns Particle: 5 µm, spherical Pore Size: 60 Å Carbon Load: proprietary End-Cap: yes Surface Area: 450 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Quat Columns Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: proprietary Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Allure Organic Acids Columns Particle: 5 µm, spherical Pore Size: 60 Å Carbon Load: proprietary End-Cap: no Surface Area: 450 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Carbamate Columns Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: proprietary Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Silica Columns (USP L3) Stationary Phase Category: bare silica (L3) Ligand Type: none Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: n/a End-Cap: n/a Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra IBD Columns (USP L68) Specialized Columns for Mixed Polar and Nonpolar Compounds Stationary Phase Category: polar-embedded alkyl (L68) Ligand Type: proprietary polar functional embedded alkyl Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 12% End-Cap: no Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Cyano Columns (USP L10) Stationary Phase Category: cyano (L10) Ligand Type: cyanopropylsilane Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 8% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Aqueous C18 Columns (USP L1) Stationary Phase Category: modified C18 (L1) Ligand Type: proprietary polar modified and functionally bonded C18 Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 15% End-Cap: no Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra C18 Columns (USP L1) Excellent for a wide range of analyses Stationary Phase Category: C18, octadecylsilane (L1) Ligand Type: monomeric C18 Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 20% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra C8 Columns (USP L7) Excellent for a wide range of analyses Stationary Phase Category: C8, octylsilane (L7) Ligand Type: monomeric C8 Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 12% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra C4 Columns (USP L26) Stationary Phase Category: C4, butylsilane (L26) Ligand Type: monomeric C4 Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 9% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra C1 Columns (USP L13) Stationary Phase Category: trimethylsilane (L13) Ligand Type: monomeric C1 Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 5% End-Cap: yes Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Ultra Amino Columns (USP L8) Stationary Phase Category: amino (L8) Ligand Type: aminopropylsilane Particle: 3 µm or 5 µm, spherical Pore Size: 100 Å Carbon Load: 2% End-Cap: no Surface Area: 300 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information
Allure Silica Columns (USP L3) Particle: 5 µm, spherical Pore Size: 60 Å Carbon Load: n/a End-cap: n/a Surface Area: 450 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C Highly retentive phase for normal phase separations. Very high surface area, Type B silica packing. View Product Information
Pinnacle DB Aqueous C18 Columns (USP L1) Stationary Phase Category: modified C18 (L1) Ligand Type: proprietary polar modified and functionally bonded C18 Particle: 1.9 µm, 3 µm, or 5 µm, spherical Pore Size: 140 Å Carbon Load: 6% End-Cap: no Surface Area: 150 m²/g pH Range: 2.5 to 8 Maximum Temperature: 80 °C View Product Information

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