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Faster LPGC-MS Phthalates Analysis Uses 67% Less Helium

Featured Application: Phthalates on LPGC Rxi-35Sil MS

  • Analyze phthalates 1.4x faster than conventional GC-MS.
  • Cut costs by reducing helium consumption 67%.
  • Pre-connected LPGC column kit prevents leaks, simplifies installation, and allows large-volume injection.

Phthalates are industrial additives that are commonly used to make plastics more flexible, and they are easily released through various degradation processes. They have become ubiquitous and are found in air, water, food, consumer products, and even the human body. Efficient methods are needed for analyzing phthalates both as raw materials and as contaminants. Phthalates analysis is typically done by conventional GC-MS using a capillary column that is 30 m or longer. However, this approach requires a high flow rate and uses a lot of helium, which is a limited and costly resource. 

Low-pressure GC-MS (LPGC-MS) is an attractive alternative because it can significantly reduce helium consumption and also speed up the analysis, improving lab productivity. As shown in Figure 1, the LPGC-MS method is 1.4x faster and uses 67% less helium than the conventional phthalates analysis. A Restek LPGC Rxi-35Sil MS column kit provides additional benefits because it is factory connected to ensure easy installation and a leak-free connection between the analytical and restrictor columns. It also has the capacity for large-volume injection, whereas narrow-bore columns can be overloaded quickly. Visit to learn more about this powerful technique.

Figure 1: Phthalates on LPGC Rxi-35Sil MS Compared to Conventional GC-MS Analysis