Pro EZGC Library Update - Azo Dye Aryl Amines

Azo dyes are commonly used in many products, including food, textiles, and paints. In some azo dyes the azo functional group (R-N=N-R’) can be broken in reductive conditions to form carcinogenic aryl amines. The use of these dyes is regulated in the EU under the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation instated by (EC) 1907/2006. We’ve shown before that the Rxi-35Sil MS is an excellent solution for the analysis of 24 aryl amines with chromatograms, and now we have updated our Pro EZGC libraries with the compounds found in the chromatogram plus some extras.

Name	CAS
1,3-Benzenediamine, 4-methoxy-	615-05-4
1,4-Benzenediamine	106-50-3
2,4,5-Trichloroaniline	636-30-6
2,4,5-Trimethylaniline	137-17-7
2,4-Diaminotoluene	95-80-7
2,4-Xylidine	95-68-1
2,6-Xylidine	87-62-7
2-Amino-4-nitrotoluene	99-55-8
2-Aminobiphenyl	90-41-5
2-Naphthylamine	91-59-8
3,3'-Dichlorobenzidine	91-94-1
3,3'-Dimethoxybenzidine	119-90-4
3,3'-Dimethylbenzidine	119-93-7
3-Chloro-o-toluidine	87-60-5
4,4'-Diaminodiphenylmethane	101-77-9
4,4'-Methylenebis(2-chloroaniline)	101-14-4
4,4'-Oxydianiline	101-80-4
4-Aminobiphenyl	92-67-1
4-Chloroaniline	106-47-8
4-Chloro-o-toluidine	95-69-2
4-Methoxy-m-phenylendiamine	614-05-4
Aniline	62-53-3
Benzenamine, 4,4'-thiobis-	139-65-1
Benzidine	92-87-5
o-Aminoazotoluene	97-56-3
o-Anisidine	90-04-0
o-Toluidine	95-53-4
p-Aminoazobenzene	60-09-3
p-Cresidine	120-71-8

	Peaks	tR	RS
		(min)
1	Aniline	1.65	29.3
2	o-Toluidine	2.06	27.7
3	2,4-Xylidine	2.5	2.1
4	2,6-Xylidine	2.54	2.1
5	o-Anisidine	2.65	6.1
6	4-Chloroaniline	2.88	12.9
7	p-Cresidine	3.21	1.9
8	2,4,5-Trimethylaniline	3.24	1.9
9	3-Chloro-o-toluidine	3.42	1.9
10	1,4-Benzenediamine	3.46	1.1
11	4-Chloro-o-toluidine	3.48	1.1
12	2,4-Diaminotoluene	4.3	29.2
13	1,3-Benzenediamine, 4-methoxy-	4.92	7.9
14	2,4,5-Trichloroaniline	5.09	7.9
15	2-Naphthylamine	5.41	1.5
16	2-Aminobiphenyl	5.44	1.5
17	2-Amino-4-nitrotoluene	5.78	15.1
18	4-Aminobiphenyl	6.59	36
19	p-Aminoazobenzene	8.24	13.8
20	4,4'-Oxydianiline	8.56	2
21	4,4'-Diaminodiphenylmethane	8.61	2
22	Benzidine	8.66	2.1
23	o-Aminoazotoluene	9.07	15.1
24	4-Methoxy-m-phenylendiamine	9.53	6.1
25	3,3'-Dimethylbenzidine	9.75	6.1
26	Benzenamine, 4,4'-thiobis-	10.64	7.7
27	4,4'-Methylenebis(2-chloroaniline)	11.03	0.2
28	3,3'-Dichlorobenzidine	11.04	0.2
29	3,3'-Dimethoxybenzidine	11.12	1.5

As seen above, EZGC provides a <12min run on the Rxi-35Sil MS with one partial and one full coelution, both of which are mass resolved.