Pure Chromatography
www.restek.com
www.restek.com
Multiclass Drug Panel on Raptor Biphenyl by LC-MS/MS
| Peaks | tR (min) | Conc. (ng/mL) | Precursor Ion | Product Ion | Product Ion | |
|---|---|---|---|---|---|---|
| 1. | trans-3-Hydroxycotinine | 1.32 | 25 | 193.1 | 80.0 | 134.0 |
| 2. | Norcotinine | 1.33 | 25 | 163.1 | 80.1 | 118.1 |
| 3. | Nicotine | 1.40 | 25 | 163.2 | 130.1 | 117.1 |
| 4. | BZP | 1.47 | 25 | 177.2 | 91.1 | 65.1 |
| 5. | Anabasine | 1.53 | 25 | 163.2 | 120.1 | 80.1 |
| 6. | Noroxymorphone | 1.78 | 25 | 288.1 | 270.1 | 212.9 |
| 7. | Lisdexamfetamine | 1.79 | 25 | 264.2 | 84.1 | 91.0 |
| 8. | Phenelzine sulfate | 1.90 | 25 | 137.2 | 105.1 | 77.1 |
| 9. | Acetaminophen | 1.93 | 100 | 152.2 | 93.0 | 65.0 |
| 10. | Pregabalin | 2.21 | 25 | 160.2 | 142.1 | 55.0 |
| 11. | Cotinine | 2.27 | 25 | 177.2 | 80.0 | 98.1 |
| 12. | Morphine | 2.27 | 25 | 286.2 | 152.1 | 165.0 |
| 13. | (+)-Ephedrine | 2.37 | 25 | 166.2 | 148.1 | 115.0 |
| 14. | Oxymorphone | 2.38 | 25 | 302.1 | 227.2 | 198.2 |
| 15. | Hydromorphone | 2.61 | 25 | 286.2 | 184.9 | 156.9 |
| 16. | Amphetamine | 2.63 | 25 | 136.2 | 91.0 | 65.1 |
| 17. | DMAA | 2.65 | 25 | 116.1 | 57.1 | 99.2 |
| 18. | Gabapentin | 2.71 | 25 | 172.2 | 154.0 | 137.1 |
| 19. | Methylephedrine | 2.83 | 25 | 180.2 | 162.0 | 115.1 |
| 20. | Levetiracetam | 2.84 | 25 | 171.1 | 125.9 | 69.2 |
| 21. | Desmethylolanzapine | 2.94 | 25 | 299.1 | 256.1 | 198.0 |
| 22. | Norcodeine | 2.96 | 25 | 286.1 | 151.9 | 115.0 |
| 23. | Olanzapine | 3.12 | 25 | 313.2 | 256.1 | 198.1 |
| 24. | Methamphetamine | 3.13 | 25 | 150.3 | 91.1 | 119.0 |
| 25. | MDA | 3.18 | 25 | 180.1 | 163.1 | 105.2 |
| 26. | (-)-Naloxone | 3.27 | 25 | 328.3 | 310.1 | 212.3 |
| 27. | Phentermine | 3.29 | 25 | 150.2 | 91.1 | 133.1 |
| 28. | Noroxycodone | 3.32 | 25 | 302.1 | 227.0 | 197.9 |
| 29. | Methylone | 3.36 | 25 | 208.1 | 160.1 | 132.1 |
| 30. | O-Desmethyl-cis-tramadol | 3.37 | 25 | 250.1 | 58.0 | 42.0 |
| 31. | (-)-Dihydrocodeine | 3.38 | 25 | 302.2 | 199.0 | 128.2 |
| 32. | Norhydrocodone | 3.43 | 25 | 286.1 | 199.0 | 128.2 |
| 33. | Codeine | 3.43 | 25 | 300.2 | 152.0 | 165.1 |
| 34. | 6-Acetylmorphine | 3.47 | 25 | 328.2 | 165.0 | 211.0 |
| 35. | MDMA | 3.60 | 25 | 194.2 | 163.0 | 135.1 |
| 36. | Desomorphine | 3.61 | 25 | 272.1 | 152.1 | 165.0 |
| 37. | Oxycodone | 3.64 | 25 | 316.2 | 298.0 | 169.0 |
| 38. | Naltrexone | 3.71 | 25 | 342.2 | 324.0 | 267.0 |
| 39. | Levamisole | 3.75 | 25 | 205.1 | 178.0 | 91.1 |
| 40. | Hydrocodone | 3.76 | 25 | 300.1 | 199.0 | 128.0 |
| 41. | Diethylpropion | 3.80 | 25 | 206.2 | 105.1 | 100.1 |
| 42. | Mephedrone | 3.80 | 25 | 178.2 | 145.0 | 160.1 |
| 43. | 2-Oxo-3-hydroxy-LSD | 3.82 | 25 | 356.3 | 237.0 | 222.0 |
| 44. | o-Desmethylvenlafaxine | 3.84 | 25 | 264.1 | 58.1 | 107.0 |
| 45. | 6-β-Naltrexol | 3.91 | 25 | 344.3 | 326.1 | 308.1 |
| 46. | Tapentadol-β-D-glucuronide | 3.91 | 25 | 398.3 | 222.1 | 107.0 |
| 47. | 7-Aminonitrazepam | 3.95 | 25 | 252.2 | 121.1 | 94.2 |
| 48. | MDEA | 4.00 | 25 | 208.1 | 163.0 | 105.2 |
| 49. | m-Hydroxybenzoylecgonine | 4.02 | 25 | 306.1 | 168.1 | 121.0 |
| 50. | Lamotrigine | 4.09 | 25 | 256.0 | 211.1 | 145.0 |
| 51. | Ritalinic acid | 4.11 | 25 | 220.1 | 84.1 | 56.2 |
| 52. | N-Desmethyltapentadol | 4.16 | 25 | 208.1 | 121.2 | 107.1 |
| 53. | Norbuprenorphine glucuronide | 4.18 | 25 | 590.5 | 414.3 | 165.0 |
| 54. | Zonisamide | 4.23 | 25 | 212.9 | 132.1 | 77.1 |
| 55. | mCPP | 4.26 | 25 | 197.1 | 154.0 | 118.1 |
| 56. | Norketamine | 4.28 | 25 | 224.1 | 125.0 | 89.1 |
| 57. | Nalbuphine | 4.33 | 25 | 358.2 | 340.1 | 115.0 |
| 58. | Norfentanyl | 4.33 | 25 | 233.1 | 84.1 | 55.0 |
| 59. | (+/-)-Hydroxybupropion | 4.35 | 25 | 256.0 | 130.2 | 166.0 |
| 60. | Tapentadol | 4.37 | 25 | 222.1 | 107.1 | 121.0 |
| 61. | Lacosamide | 4.47 | 25 | 251.5 | 91.1 | 108.1 |
| 62. | Dextrorphan | 4.50 | 25 | 258.2 | 157.0 | 201.2 |
| 63. | Levorphanol | 4.50 | 25 | 258.2 | 156.8 | 199.2 |
| 64. | 7-Hydroxyquetiapine | 4.51 | 25 | 400.3 | 269.0 | 208.0 |
| 65. | Molindone | 4.51 | 25 | 277.2 | 100.1 | 70.2 |
| 66. | Tramadol | 4.52 | 25 | 264.2 | 58.0 | 77.1 |
| 67. | Zolpidem phenyl-4-carboxylic acid | 4.60 | 25 | 338.2 | 265.1 | 219.0 |
| 68. | Felbamate | 4.62 | 25 | 239.1 | 117.1 | 177.8 |
| 69. | N-Desmethyl-cis-tramadol | 4.65 | 25 | 250.2 | 44.0 | 232.1 |
| 70. | Ketamine | 4.66 | 25 | 238.1 | 125.1 | 89.1 |
| 71. | Benzoylecgonine | 4.67 | 25 | 290.1 | 168.1 | 77.1 |
| 72. | Methylphenidate | 4.68 | 25 | 234.1 | 84.1 | 56.1 |
| 73. | Normeperidine | 4.76 | 25 | 234.1 | 160.2 | 91.0 |
| 74. | Meprobamate | 4.79 | 25 | 219.1 | 158.2 | 97.0 |
| 75. | Meperidine | 4.80 | 25 | 248.1 | 220.1 | 174.1 |
| 76. | Bupropion | 4.81 | 25 | 240.0 | 184.1 | 130.2 |
| 77. | Heroin | 4.85 | 25 | 370.4 | 328.2 | 164.9 |
| 78. | Cocaine | 5.01 | 25 | 304.2 | 182.0 | 77.1 |
| 79. | 7-Aminoclonazepam | 5.02 | 25 | 286.1 | 121.2 | 250.1 |
| 80. | Zopiclone | 5.04 | 25 | 389.2 | 245.0 | 217.2 |
| 81. | N-Desmethylmirtazapine | 5.10 | 25 | 252.1 | 195.1 | 209.2 |
| 82. | Norcocaine | 5.11 | 25 | 290.1 | 168.0 | 136.1 |
| 83. | Phenobarbital* | 5.11 | 500 | 230.9 | 187.8 | 85.0 |
| 84. | Buprenorphine glucuronide | 5.12 | 25 | 644.3 | 468.2 | 55.1 |
| 85. | MDPV | 5.15 | 25 | 276.2 | 135.1 | 126.1 |
| 86. | Venlafaxine | 5.15 | 25 | 278.4 | 260.4 | 121.2 |
| 87. | Milnacipran | 5.24 | 25 | 247.2 | 100.1 | 129.1 |
| 88. | Pentazocine | 5.29 | 25 | 286.2 | 218.1 | 69.2 |
| 89. | Mirtazapine | 5.31 | 25 | 266.1 | 195.1 | 72.1 |
| 90. | Butalbital* | 5.31 | 500 | 223.0 | 180.0 | 84.9 |
| 91. | Norbuprenorphine | 5.35 | 50 | 414.3 | 152.2 | 165.2 |
| 92. | LSD | 5.39 | 25 | 324.3 | 223.1 | 208.0 |
| 93. | Butorphanol | 5.43 | 25 | 328.3 | 310.3 | 131.2 |
| 94. | Fosphenytoin | 5.43 | 25 | 363.1 | 265.9 | 207.8 |
| 95. | Topiramate | 5.44 | 25 | 340.2 | 264.2 | 223.9 |
| 96. | Cocaethylene | 5.48 | 25 | 318.2 | 196.1 | 82.0 |
| 97. | Clozapine | 5.48 | 25 | 328.2 | 271.1 | 193.1 |
| 98. | 9-Hydroxyrisperidone | 5.51 | 25 | 427.3 | 207.1 | 110.2 |
| 99. | Acetyl fentanyl | 5.58 | 25 | 323.3 | 188.0 | 105.0 |
| 100. | Didesmethyl citalopram HCl | 5.73 | 25 | 297.1 | 261.9 | 109.1 |
| 101. | 7-Aminoflunitrazepam | 5.75 | 25 | 284.1 | 135.0 | 227.1 |
| 102. | Amobarbital* | 5.75 | 500 | 225.0 | 182.0 | 84.8 |
| 103. | Zolpidem | 5.76 | 25 | 308.2 | 235.2 | 218.9 |
| 104. | N-Desmethylcitalopram | 5.77 | 25 | 311.1 | 262.1 | 109.1 |
| 105. | Isocarboxazid | 5.77 | 25 | 232.0 | 91.1 | 65.2 |
| 106. | Pentobarbital* | 5.79 | 500 | 225.0 | 182.0 | 84.9 |
| 107. | Escitalopram | 5.80 | 25 | 325.3 | 109.1 | 261.9 |
| 108. | Citalopram | 5.80 | 25 | 325.2 | 109.1 | 262.0 |
| 109. | Diphenhydramine | 5.80 | 25 | 256.1 | 167.0 | 152.1 |
| 110. | Desmethyldoxepin | 5.88 | 25 | 266.1 | 107.1 | 115.0 |
| 111. | Ezogabine | 5.91 | 25 | 304.0 | 230.1 | 109.1 |
| 112. | Doxepin | 5.96 | 25 | 280.1 | 107.2 | 77.1 |
| 113. | Haloperidol | 5.96 | 25 | 377.2 | 123.0 | 95.1 |
| 114. | Fluvoxamine | 5.97 | 25 | 319.3 | 71.1 | 257.8 |
| 115. | Trazodone | 5.99 | 25 | 372.3 | 176.1 | 148.0 |
| 116. | Norfluoxetine | 6.01 | 25 | 296.3 | 134.3 | 104.9 |
| 117. | Fentanyl | 6.02 | 25 | 337.3 | 188.0 | 105.1 |
| 118. | Oxcarbazepine | 6.02 | 25 | 253.1 | 180.0 | 208.1 |
| 119. | Risperidone | 6.03 | 25 | 411.2 | 191.0 | 110.1 |
| 120. | Buprenorphine | 6.04 | 50 | 468.3 | 55.1 | 414.2 |
| 121. | Fluoxetine | 6.05 | 25 | 310.1 | 148.0 | 115.1 |
| 122. | Secobarbital* | 6.08 | 500 | 237.0 | 193.9 | 84.8 |
| 123. | Phenytoin | 6.12 | 25 | 253.0 | 103.9 | 181.7 |
| 124. | Carisoprodol | 6.13 | 25 | 261.1 | 176.0 | 62.0 |
| 125. | Flurazepam | 6.14 | 25 | 388.2 | 315.2 | 183.0 |
| 126. | Chlordiazepoxide | 6.14 | 25 | 300.1 | 282.0 | 227.0 |
| 127. | Dextromethorphan | 6.16 | 25 | 272.2 | 215.1 | 170.9 |
| 128. | PCP | 6.18 | 25 | 244.2 | 86.1 | 159.1 |
| 129. | Tenoxicam | 6.18 | 25 | 338.1 | 121.0 | 95.0 |
| 130. | Buspirone | 6.20 | 25 | 386.3 | 122.1 | 95.0 |
| 131. | Quetiapine | 6.28 | 25 | 384.2 | 253.0 | 221.2 |
| 132. | Norpropoxyphene | 6.29 | 25 | 326.4 | 252.0 | 91.1 |
| 133. | Propoxyphene | 6.30 | 25 | 340.3 | 265.9 | 58.1 |
| 134. | Asenapine | 6.35 | 25 | 286.2 | 165.1 | 229.1 |
| 135. | Ziprasidone | 6.40 | 25 | 413.2 | 194.1 | 130.0 |
| 136. | Protriptyline | 6.42 | 25 | 264.1 | 191.1 | 165.2 |
| 137. | Promazine | 6.42 | 25 | 285.1 | 58.0 | 86.0 |
| 138. | Midazolam | 6.43 | 25 | 326.2 | 291.1 | 248.9 |
| 139. | Desipramine | 6.43 | 25 | 267.1 | 72.1 | 193.1 |
| 140. | Amoxapine | 6.44 | 25 | 314.2 | 271.0 | 193.1 |
| 141. | Sufentanil | 6.48 | 25 | 387.2 | 238.1 | 111.1 |
| 142. | Imipramine | 6.51 | 25 | 281.1 | 86.2 | 58.1 |
| 143. | Paroxetine | 6.51 | 25 | 330.2 | 192.2 | 70.1 |
| 144. | Loxapine | 6.52 | 25 | 328.1 | 271.1 | 193.0 |
| 145. | Maprotiline | 6.52 | 25 | 278.1 | 250.2 | 191.0 |
| 146. | Duloxetine | 6.52 | 25 | 298.1 | 154.1 | 188.2 |
| 147. | Metaxalone | 6.52 | 25 | 222.1 | 161.1 | 77.1 |
| 148. | Carbamazepine | 6.55 | 10 | 237.1 | 194.1 | 165.0 |
| 149. | Cyclobenzaprine | 6.56 | 25 | 276.2 | 215.0 | 189.0 |
| 150. | EDDP | 6.57 | 25 | 278.2 | 234.3 | 249.2 |
| 151. | Nortriptyline | 6.58 | 25 | 264.1 | 91.1 | 115.2 |
| 152. | Mitragynine | 6.59 | 25 | 399.3 | 174.2 | 159.0 |
| 153. | Eslicarbazepine | 6.60 | 25 | 297.2 | 194.0 | 237.1 |
| 154. | Amitriptyline | 6.65 | 25 | 278.1 | 91.1 | 202.1 |
| 155. | α-Hydroxymidazolam | 6.70 | 25 | 342.2 | 324.1 | 202.9 |
| 156. | Trimipramine | 6.75 | 25 | 295.2 | 100.2 | 58.2 |
| 157. | N-Desmethylflunitrazepam | 6.80 | 25 | 300.1 | 254.1 | 198.1 |
| 158. | Lorazepam | 6.82 | 25 | 321.1 | 275.0 | 229.0 |
| 159. | Mesoridazine | 6.83 | 25 | 387.2 | 126.1 | 98.2 |
| 160. | Tiagabine | 6.89 | 25 | 376.2 | 246.8 | 111.1 |
| 161. | Ketorolac | 6.90 | 25 | 256.1 | 104.9 | 77.0 |
| 162. | Chlorpromazine | 6.91 | 25 | 320.1 | 58.1 | 86.1 |
| 163. | Loxoprofen* | 6.93 | 200 | 245.0 | 83.2 | 80.9 |
| 164. | Clomipramine | 6.95 | 25 | 315.3 | 86.0 | 58.0 |
| 165. | Oxazepam | 6.96 | 25 | 287.1 | 241.2 | 268.8 |
| 166. | Methadone | 6.98 | 25 | 310.2 | 264.9 | 105.1 |
| 167. | Sertraline | 6.98 | 25 | 306.2 | 158.9 | 275.1 |
| 168. | Dehydro aripiprazole | 7.01 | 25 | 446.2 | 285.0 | 98.1 |
| 169. | Clonazepam | 7.01 | 25 | 316.1 | 270.0 | 214.1 |
| 170. | Nitrazepam | 7.01 | 25 | 282.1 | 235.9 | 180.1 |
| 171. | Lornoxicam | 7.02 | 100 | 373.1 | 121.1 | 95.0 |
| 172. | 25I-NBOMe | 7.05 | 25 | 428.1 | 121.2 | 91.1 |
| 173. | Salsalate* | 7.05 | 100 | 256.8 | 136.8 | 92.9 |
| 174. | Desalkylflurazepam | 7.09 | 25 | 289.0 | 140.1 | 104.0 |
| 175. | Tolmetin | 7.10 | 25 | 258.1 | 119.1 | 91.0 |
| 176. | α-Hydroxytriazolam | 7.12 | 25 | 359.1 | 330.9 | 175.9 |
| 177. | Fluphenazine | 7.16 | 25 | 438.3 | 171.1 | 143.2 |
| 178. | 2-Hydroxyethylflurazepam | 7.16 | 25 | 333.1 | 211.1 | 109.0 |
| 179. | Ketoprofen* | 7.17 | 100 | 253.0 | 209.0 | - |
| 180. | Naproxen* | 7.17 | 200 | 229.0 | 168.9 | 184.9 |
| 181. | EMDP | 7.19 | 25 | 264.2 | 235.2 | 220.3 |
| 182. | Aripiprazole | 7.20 | 25 | 448.2 | 285.0 | 176.1 |
| 183. | Perphenazine | 7.22 | 25 | 404.2 | 171.1 | 143.2 |
| 184. | Etoricoxib | 7.24 | 25 | 359.2 | 280.0 | 279.2 |
| 185. | Methaqualone | 7.24 | 25 | 251.1 | 91.1 | 132.2 |
| 186. | α-Hydroxyalprazolam | 7.25 | 25 | 325.1 | 297.0 | 216.2 |
| 187. | Trifluoperazine | 7.28 | 25 | 408.2 | 141.2 | 113.1 |
| 188. | Piroxicam | 7.34 | 25 | 332.1 | 95.2 | 78.1 |
| 189. | Ibuprofen* | 7.34 | 200 | 205.0 | 160.9 | - |
| 190. | Prochlorperazine | 7.36 | 25 | 374.1 | 141.0 | 113.1 |
| 191. | Etodolac* | 7.36 | 50 | 286.0 | 241.9 | 212.0 |
| 192. | Nordiazepam | 7.37 | 25 | 271.0 | 139.9 | 208.0 |
| 193. | Phenazepam | 7.39 | 25 | 349.1 | 206.2 | 179.0 |
| 194. | Fenoprofen* | 7.40 | 200 | 240.9 | 92.8 | - |
| 195. | Zaleplon | 7.43 | 25 | 306.1 | 264.0 | 236.0 |
| 196. | Clobazam | 7.43 | 25 | 301.0 | 259.1 | 224.0 |
| 197. | Flurbiprofen* | 7.48 | 200 | 243.0 | 199.0 | 196.8 |
| 198. | Thiothixene | 7.50 | 25 | 444.2 | 221.2 | 235.0 |
| 199. | Flunitrazepam | 7.55 | 25 | 314.2 | 267.9 | 239.1 |
| 200. | Meloxicam | 7.55 | 25 | 352.1 | 115.0 | 141.0 |
| 201. | Triazolam | 7.58 | 25 | 343.1 | 307.9 | 315.0 |
| 202. | Estazolam | 7.58 | 25 | 295.1 | 266.9 | 205.1 |
| 203. | Celecoxib | 7.60 | 25 | 382.2 | 362.0 | 300.1 |
| 204. | Parecoxib | 7.60 | 25 | 371.2 | 234.0 | 165.1 |
| 205. | Temazepam | 7.61 | 25 | 301.1 | 255.1 | 282.9 |
| 206. | Sulindac | 7.70 | 25 | 357.2 | 233.1 | 248.0 |
| 207. | Alprazolam | 7.72 | 25 | 309.1 | 280.9 | 204.9 |
| 208. | Flufenamic acid* | 7.75 | 50 | 279.9 | 236.1 | 176.2 |
| 209. | Thioridazine | 7.76 | 25 | 371.2 | 126.1 | 98.1 |
| 210. | Diclofenac* | 7.78 | 100 | 293.9 | 249.8 | - |
| 211. | Nabumetone | 7.80 | 25 | 229.1 | 171.1 | 128.1 |
| 212. | Oxaprozin | 7.87 | 25 | 294.1 | 103.0 | 234.2 |
| 213. | HU-211 | 8.03 | 25 | 387.3 | 155.9 | 128.1 |
| 214. | JWH‐200 | 8.04 | 25 | 385.3 | 155.0 | 127.1 |
| 215. | Diazepam | 8.04 | 25 | 285.1 | 192.9 | 153.9 |
| 216. | Mefenamic acid | 8.04 | 25 | 242.1 | 224.1 | - |
| 217. | Tolfenamic acid* | 8.17 | 50 | 259.9 | 215.8 | - |
| 218. | Meclofenamic acid* | 8.18 | 200 | 293.9 | 257.8 | 177.7 |
| 219. | (+/-)-CP 47,497* | 8.27 | 200 | 317.1 | 245.1 | 159.0 |
| 220. | Indomethacin* | 8.29 | 50 | 356.0 | 311.8 | 296.9 |
| 221. | Perampanel | 8.32 | 25 | 350.2 | 219.1 | 247.1 |
| 222. | (+/-)-CP 47,497 C8 homologue* | 8.42 | 200 | 331.1 | 259.0 | 159.1 |
| 223. | 11-Nor-9-carboxy-delta-9-THC* | 8.44 | 25 | 343.0 | 298.9 | 244.8 |
| 224. | Prazepam | 8.51 | 25 | 325.2 | 271.0 | 139.9 |
| 225. | XLR-11 | 8.60 | 25 | 330.3 | 125.2 | 144.0 |
| 226. | Δ9-THC | 8.76 | 25 | 315.2 | 193.0 | 123.2 |
| 227. | UR-144 | 8.78 | 25 | 312.3 | 125.1 | 214.1 |
| 228. | JWH-250 | 8.96 | 25 | 336.3 | 120.9 | 91.1 |
| 229. | THCA-A* | 9.12 | 25 | 357.1 | 312.9 | 245.0 |
| 230. | JWH-073 | 9.21 | 25 | 328.2 | 155.0 | 127.1 |
| 231. | JWH‐018 | 9.35 | 25 | 342.3 | 127.1 | 155.1 |
*Analyzed using negative polarity.
LC_CF0621
| Column | Raptor Biphenyl (cat.# 9309A12) | ||||||||||||||||||||||||
| Dimensions: | 100 mm x 2.1 mm ID | ||||||||||||||||||||||||
| Particle Size: | 2.7 µm | ||||||||||||||||||||||||
| Guard Column: | Raptor Biphenyl EXP guard column cartridge 5 mm, 2.1 mm ID, 2.7 µm (cat.# 9309A0252) | ||||||||||||||||||||||||
| Temp.: | 30 °C | ||||||||||||||||||||||||
| Sample | |||||||||||||||||||||||||
| Diluent: | Water | ||||||||||||||||||||||||
| Inj. Vol.: | 5 µL | ||||||||||||||||||||||||
| Mobile Phase | |||||||||||||||||||||||||
| A: | Water + 0.1% formic acid + 2 mM ammonium formate | ||||||||||||||||||||||||
| B: | Methanol + 0.1% formic acid + 2 mM ammonium formate | ||||||||||||||||||||||||
| |||||||||||||||||||||||||
| Detector | MS/MS | ||||||||||||||||||||||||
| Ion Mode: | ESI+/ESI- | ||||||||||||||||||||||||
| Mode: | Scheduled MRM | ||||||||||||||||||||||||
| Instrument | UHPLC | ||||||||||||||||||||||||
| Notes | 1. Positive and negative polarity data were collected simultaneously from a single injection. 2. Ibuprofen, fosphenytoin, and topiramate degrade quickly in solution. 3. Levorphanol and dextrorphan are enantiomers and are not resolved. 4. Escitalopram is a pure enantiomer and citalopram is a racemic mixture of both enantiomers. These compounds are not resolved. 5. DMAA consists of 4 stereoisomers, 2 of which are partially resolved. 6. Doxepin and desmethylydoxepin consist of a mixture of cis/trans isomers. The isomers are fully resolved and the retention time identifies the main isomer component. 7. Lornoxicam, meloxicam, etodolac, oxaprozin, indomethacin, and mefenamic acid can be detected by positive or negative polarity. The polarity chosen in this chromatogram provides optimal response. |
Printing tips! To print chromatograms full page, change the print settings in the print dialogue window of your PDF reader software: 1) "fit" or "fit to page", 2) "landscape" for wide chromatograms or "portrait" for tall chromatograms.
Restek Corporation, U.S., 110 Benner Circle, Bellefonte, PA 16823
Copyright © 2018 Restek Corporation. All rights reserved.
A Company of Owners
Cookies allow for a variety of features that make your visit to Restek more enjoyable. By using this website, you agree to the use of cookies in accordance with our guidelines. For more information, see our privacy policy.
Restek Corporation, U.S., 110 Benner Circle, Bellefonte, PA 16823
Copyright © 2018 Restek Corporation. All rights reserved.
A Company of Owners
Cookies allow for a variety of features that make your visit to Restek more enjoyable. By using this website, you agree to the use of cookies in accordance with our guidelines. For more information, see our privacy policy.