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Pro EZGC Library Update - Azo Dye Aryl Amines

By
  • Jason Hoisington
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Azo dyes are commonly used in many products, including food, textiles, and paints. In some azo dyes the azo functional group (R-N=N-R’) can be broken in reductive conditions to form carcinogenic aryl amines. The use of these dyes is regulated in the EU under the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation instated by (EC) 1907/2006. We’ve shown before that the Rxi-35Sil MS is an excellent solution for the analysis of 24 aryl amines with chromatograms (https://www.restek.com/Technical-Resources/Technical-Library/General-Interest/GN_GNAR2515-UNV), and now we have updated our Pro EZGC libraries with the compounds found in the chromatogram plus some extras.

 

Name CAS
1,3-Benzenediamine, 4-methoxy- 615-05-4
1,4-Benzenediamine 106-50-3
2,4,5-Trichloroaniline 636-30-6
2,4,5-Trimethylaniline 137-17-7
2,4-Diaminotoluene 95-80-7
2,4-Xylidine 95-68-1
2,6-Xylidine 87-62-7
2-Amino-4-nitrotoluene 99-55-8
2-Aminobiphenyl 90-41-5
2-Naphthylamine 91-59-8
3,3'-Dichlorobenzidine 91-94-1
3,3'-Dimethoxybenzidine 119-90-4
3,3'-Dimethylbenzidine 119-93-7
3-Chloro-o-toluidine 87-60-5
4,4'-Diaminodiphenylmethane 101-77-9
4,4'-Methylenebis(2-chloroaniline) 101-14-4
4,4'-Oxydianiline 101-80-4
4-Aminobiphenyl 92-67-1
4-Chloroaniline 106-47-8
4-Chloro-o-toluidine 95-69-2
4-Methoxy-m-phenylendiamine 614-05-4
Aniline 62-53-3
Benzenamine, 4,4'-thiobis- 139-65-1
Benzidine 92-87-5
o-Aminoazotoluene 97-56-3
o-Anisidine 90-04-0
o-Toluidine 95-53-4
p-Aminoazobenzene 60-09-3
p-Cresidine 120-71-8
 



Peaks tR RS
(min)
1 Aniline 1.65 29.3
2 o-Toluidine 2.06 27.7
3 2,4-Xylidine 2.5 2.1
4 2,6-Xylidine 2.54 2.1
5 o-Anisidine 2.65 6.1
6 4-Chloroaniline 2.88 12.9
7 p-Cresidine 3.21 1.9
8 2,4,5-Trimethylaniline 3.24 1.9
9 3-Chloro-o-toluidine 3.42 1.9
10 1,4-Benzenediamine 3.46 1.1
11 4-Chloro-o-toluidine 3.48 1.1
12 2,4-Diaminotoluene 4.3 29.2
13 1,3-Benzenediamine, 4-methoxy- 4.92 7.9
14 2,4,5-Trichloroaniline 5.09 7.9
15 2-Naphthylamine 5.41 1.5
16 2-Aminobiphenyl 5.44 1.5
17 2-Amino-4-nitrotoluene 5.78 15.1
18 4-Aminobiphenyl 6.59 36
19 p-Aminoazobenzene 8.24 13.8
20 4,4'-Oxydianiline 8.56 2
21 4,4'-Diaminodiphenylmethane 8.61 2
22 Benzidine 8.66 2.1
23 o-Aminoazotoluene 9.07 15.1
24 4-Methoxy-m-phenylendiamine 9.53 6.1
25 3,3'-Dimethylbenzidine 9.75 6.1
26 Benzenamine, 4,4'-thiobis- 10.64 7.7
27 4,4'-Methylenebis(2-chloroaniline) 11.03 0.2
28 3,3'-Dichlorobenzidine 11.04 0.2
29 3,3'-Dimethoxybenzidine 11.12 1.5
As seen above, EZGC provides a <12min run on the Rxi-35Sil MS with one partial and one full coelution, both of which are mass resolved.

 





For more information on Azo dyes, see our previous work at https://www.restek.com/Technical-Resources/Technical-Library/General-Interest/GN_GNAR2515-UNV.