I’ve used ezGC Modeling Software since 1997 and have heard quite a bit of dialog on its utility. ezGC allows a user to enter two different retention times on a given column and use that data to adjust: carrier gas type, flow (constant flow / constant pressure), temperature, column length, film thickness, column ID, and pre-column (guard column)...this can be done simultaneously. It also has advanced features that allow adjustments to peak widths & response that can replicate what you would expect to see on your GC. The actual GC runs below give you an idea of the utility of ezGC; a slow program would not work, a fast program has coelutions and the modeled ezGC suggested solution works. I have attached a link to the whole chromatogram and it’s clear it would take a lifetime to get these analytes resolved without this program. Yes there are a few bugs here and there, but once you realized the absolute power of this program you will see it as Heaven-sent. (Cat#21487)
Szopa, C., R. Sternberg, D. Coscia, H. Cottin, F. Raulin, F. Goesmann, H. Rosenbauer. Gas Chromatography for in situ analysis of a cometary nucleus: characterization of diphenyl / dimethylpolysiloxane stationary phases: J. Chrom. A. 1999. 863: 157-169
Matevz, P., J.M. Davis, C.D.Samuel. Prediction of Thermodynamic Parameters in Gas Chromatography from Molecular Structure: Hydrocarbons. J. Chem. Inf. Comput. Sci. 2004. 44: 399-409.
Samuel C., J.M. Davis. Application of statistical-overlap theory to gas chromatograms simulated on nonpolar stationary phases with commercial software: J. Chrom. A. 1999: 842: 65-77.