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One Analysis, One Column, Less than 9 Minutes for Over 60 Multiclass Antibiotics

Featured Application: Multiclass Veterinary Antibiotics on Raptor C18 by LC-MS/MS

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  • Highly efficient peak separation and fast analysis times.
  • Versatility and global applicability for antibiotic residue analysis—capable of individual class panel optimization for quantitation:
    • Macrolide, Lincosamide, and Streptogramin (Figure 1)
    • Amphenicol and Tetracycline (Figure 2)
    • Quinolone (Figure 3)
    • Penicillin, Cephalosporin, and Tetracycline (Figure 4)
    • Sulfonamide (Figure 5) (For Ionophore, use on Raptor Biphenyl. [Figure 6])

The use of antibiotics on food-producing animals is a public health and safety concern due to the potential of generating drug-resistant bacteria. Many countries in the European Union and Canada have banned the use of antibiotics for nontherapeutic purposes, and the United States is implementing a policy to reduce the use of medically important antibiotics for growth promotion. To regulate the proper use of veterinary antibiotics, the U.S. FDA has set maximum residue limits (MRL) for a variety of animal tissue and food products (21 CFR Part 556). A sensitive, efficient, and reliable analytical method for different classes of antibiotics is necessary to meet this regulation, and the Raptor C18 LC column is the ideal choice.

 

 

Figure 1: Macrolide, Lincosamide, and Streptogramin Antibiotics on Raptor C18 by LC-MS/MS

 

 

Figure 2: Amphenicol and Tetracycline Antibiotics on Raptor C18 by LC-MS/MS

 

 

Figure 3: Quinolone Antibiotics on Raptor C18 by LC-MS/MS

 

 

Figure 4: Penicillin, Cephalosporin, and Tetracycline Antibiotics on Raptor C18 by LC-MS/MS

 

 

Figure 5: Sulfonamide Antibiotics on Raptor C18 by LC-MS/MS

 

 

Figure 6: Ionophore Antibiotics on Raptor Biphenyl by LC-MS/MS

 
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