Nitrosamines on Rxi-624Sil MS

	Peaks	t_R (min)	Conc. (ng/mL)	Precursor Ion	Product Ion	Collision Energy	Confirmation Precursor Ion	Confirmation Product Ion	Collision Energy
1.	N-Nitrosodimethylamine (NDMA)	4.48	120	74	42	18	74	43	12
2.	N-Nitrosodimethylamine-d6 (NDMA-d6)	4.48	150	80	46	15	80	48	10
3.	N-Nitrosomethylethylamine (NMEA)	5.08	120	88	42	16	88	43	8
4.	N-Nitrosodiethylamine (NDEA)	5.56	120	102	44	12	102	56	14
5.	N-Nitrosoethylisopropylamine (NEIPA)	5.96	120	116	44	12	116	99	6
6.	N-Nitroso-diisopropylamine (NDIPA)	6.31	128	130	71	12	130	88	6
7.	Methylaniline (NMPA)	6.53	131	107	77	26	106	77	14
8.	N-Nitroso-di-n-propylamine (NDPA)	6.62	120	130	85	8	130	113	6
9.	N-Nitrosomorpholine (NMOR)	6.71	120	116	56	10	116	86	6
10.	N-Nitrosopyrrolidine (NPYR)	6.79	120	100	55	6	100	68	8
11.	N-Nitrosopiperidine (NPIP)	7.02	120	114	69	6	114	84	8
12.	N-Nitrosodi-n-butylamine (NDBA)	7.65	120	158	99	8	116	99	6
13.	N-Nitroso-N-methyl-4-aminobutyric acid (NMBA)	8.02	365	130	70	10	130	98	5
14.	Phenylbenzeneamine (NDPHA)	9.36	120	169	66	22	168	139	36

Injection
Column	Rxi-624SilMS, 30 m, 0.25 mm ID, 1.4 µm (cat.# 13868)
Standard/Sample	Nitrosamine calibration mix, Method 521 (cat.# 31898)
	N-Nitrosodimethylamine-d6 (cat.# 33910)
	N-Nitrosodiphenylamine (cat.# 31429)
	N-Nitroso-methylphenylamine
	N-Nitroso-diisopropylamine
	N-Nitrosoethylisopropylamine
	N-Nitrosomorpholine

Diluent:	Methanol
Inj. Vol.:	1 µL split (split ratio 10:1)
Liner:	Topaz 4.0 mm ID straight inlet liner w/ wool (cat.# 23444)
Inj. Temp.:	280 °C
Oven
Oven Temp.:	40 °C (hold 0.5 min) to 320 °C at 30 °C/min (hold 7 min)
Carrier Gas	He, constant flow
Flow Rate:	1.2 mL/min

Detector	MS
Mode:	SIM
Transfer Line Temp.:	280 °C
Analyzer Type:	Quadrupole
Source Temp.:	325 °C
Instrument	Thermo Scientific TSQ 8000 Triple Quadrupole GC-MS
Notes	For N-nitroso-methylphenylamine (NMPA) and N-nitrosodiphenylamine (NDPHA), the nitroso groups are cleaved in the inlet to form methylaniline and phenylbenzeneamine, respectively.

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