Concern over persistent organic pollutants, or POPs, only continues to grow. Analytically, these compounds also present a lot of challenges requiring consistency while achieving ultralow-level sensitivity. On Thursday, September 24, Restek’s Chris Rattray is presenting the webinar “Persistent Ongoing Perfection: Optimization of a GC-MS/MS Method for the Analysis of POPs Plus an Alternate Approach Utilizing High-resolution Mass Spectrometry” along with a team of industry experts as part of Thermo Fisher Scientific’s Environmental Webinar Week.
Mycotoxins are toxic secondary metabolite compounds produced by mold or fungi. Due to the toxicity of certain mycotoxins that can be found on cannabis plants, there is a growing need to detect their presence in both raw plant materials and finished cannabis products.
These new reference standards enable labs to expand their cannabis analyses with a Restek solution when coupled with our high-throughput Raptor ARC-18 (cat.# 9314A12) LC column.
For mycotoxins and other reference standards, Raptor LC columns, sample preparation products, and the expert consultation your cannabis lab needs, turn to www.restek.com/cannabis
Author(s): Sharon A. Lupo, Randall L. Romesberg, Xiaoning Lu
Published By: Journal of Chromatography A
Year of Publication: 2020
Abstract: An automated inline sample preparation (ILSP) method has been developed for pesticide residue analysis in spinach by LC-MS/MS. Chlorophyll pigments and other matrix constituents were removed from the sample extract using a UHPLC system equipped with an auxiliary pump, 6-port high pressure switching valve, and dual-directional ILSP cartridge containing bonded silica. The new procedure was evaluated as an entirely separate workflow using a simple solid-liquid extraction and as part of a cleanup strategy in conjunction with QuEChERS. Accuracy and precision experiments were conducted in spinach at two concentration levels (n=6). Of the 63 pesticides tested, 86% (0.005 mg/kg) and 100% (0.05 mg/kg) displayed average recoveries within 70-120% and RSD values ≤20% for the ILSP method. In addition, low to moderate matrix effects (<50%) were calculated for 95% of the analytes. Overall performance of the proposed method was found to be better or comparable to a traditional QuEChERS procedure utilizing AOAC formulated salts and dSPE sorbents, while significantly reducing the amount of pigments reaching the MS source. The ILSP workflow is a simpler procedure with fewer steps that require less time than traditional extraction and cleanup techniques.
Cannabidivarinic Acid (CBDVA) is a non-psychoactive cannabinoid reported to have anti-inflammatory properties. While its medicinal benefits are still being researched, quantifying this compound in cannabis samples is crucial for obtaining a true measurement of potency and chemovar identification. Restek now offers a new CBDVA certified reference material (CRM) to help labs advance their analysis of cannabis.
Restek’s new CBDVA standard is ideal for creating multipoint (5-point minimum suggested) calibration curves for LC analysis. With verified composition and stability, this prepared stock product eliminates the need for in-house standards preparation for greater convenience and lower labor requirements. As it’s excluded from U.S. DEA Controlled Substances Act (CSA) regulatory controls, no customer permits or licensing required to purchase within the U.S., and because it’s manufactured and QC tested in Restek’s ISO-accredited labs, this new CBDVA standard qualifies as a certified reference material (CRM) that satisfies your ISO requirements.
Restek Corporation has several positions open in Bellefonte, PA, for Operations Technicians in our Final Assembly, Liners, Reference Standards, Quality Control (QC), and Shipping/Receiving departments. Various work schedules are available: Monday through Friday from 3:00 p.m. to 11:30 p.m.; Monday through Friday from 8:45 a.m. to 5:15 p.m.; and Sunday through Thursday from 10:00 p.m. to 6:30 a.m.
Recognized throughout Centre County and beyond as a premier employer, Restek is a 100% employee-owned company with a people-centric and empowered culture that sets it apart from the rest of the industry. Living by its Core Values and Philosophy, the company continues to be its customers’ first and best choice for chromatography. You can learn more about what makes Restek such a great place to work at www.restek.com/philosophy
Do you think you would be a good fit with Restek and its unique culture? If so, then you are an ideal candidate. Visit Restek at 110 Benner Circle in Bellefonte, PA, on Tuesday, February 27, between noon and 5:00 p.m. Be sure to bring 3 copies of your résumé, a list of at least 3 professional references, and your driver’s license. The event will use an open interview format, so while there may be a wait, each candidate will receive individual and appropriate attention.
Find the full job descriptions at www.restek.com/jobs Applicants are encouraged to attend this open interview, but if unable, applicants can also apply through the website.
Restek is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status.
Restek has expanded its line of Resprep solid phase extraction (SPE) products with the addition of polymeric sorbents, available in both cartridges for high loading capacity and 96-well plates for high throughput and automation.
Because Resprep polymeric SPE products feature a silica-free, bonded polymeric material, there are no unwanted secondary silica interactions, even with basic compounds. Their high surface area means a higher loading capacity compared to silica sorbents, and their stability over a wide pH range (0–14) means they won’t hydrolyze under extreme conditions. New Resprep polymeric SPE cartridges and 96-well plates are water-wettable, allowing for streamlined conditioning and equilibration steps to drastically reduce solvent usage and sample prep time. And they are not flow-rate dependent, so they maintain retention and capacity after conditioning, even if dried out from vacuum or positive pressure flows.
Resprep polymeric SPE products offer five distinct packings to choose from. Find them all, and the entire line of Resprep sample preparation products, at www.restek.com/resprep
Cannabicyclol (CBL) is formed through the photodegradation of cannabichromene (CBC). Levels are typically quite low, and the medicinal benefits of CBL are still being researched, but quantifying this compound in cannabis samples is crucial for obtaining a more-complete cannabinoids profile. Restek has just released a new CBL certified reference material (CRM) to further aid labs in the comprehensive characterization of cannabis: www.restek.com/catalog/view/54615
Restek’s new CBL standard is ideal for creating multipoint (5-point minimum suggested) calibration curves for LC analysis. With verified composition and stability, this prepared stock product eliminates the need for in-house standards preparation for greater convenience and lower labor requirements. As a U.S. DEA-exempted formulation, no additional customer permits or licensing are required to purchase within the U.S., and because it’s manufactured and QC tested in Restek’s ISO-accredited labs, this new CBL standard qualifies as a certified reference material (CRM) that satisfies your ISO requirements.
For CBL and other reference standards, Raptor LC columns, sample preparation products, and the expert consultation your cannabis lab needs, turn to www.restek.com/cannabis
Before you go to Gulf Coast Conference 2019, visit our conference page to learn what we’ll be doing, to easily contact us with any questions you may have, and to access the conference’s website for additional event details.