Rtx-Wax: A Rugged and Reliable Choice for the Analysis of Glycols in Water

Author: Corby Hilliard and Chris English

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAR3086-UNV

Abstract: Three types of polyethylene glycol (PEG) columns from different vendors were evaluated to determine which performed best for the analysis of glycols in water. The columns were first challenged with exposure to 600 aqueous injections and then linearity, lifetime, and bleed were assessed. Rtx-Wax columns performed well throughout the test and were the only columns that passed all tests.

 

Using a Methanizer for CO and CO2 Analysis at Low Levels

Author: Mark Badger

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/General-Interest/gen_GNAR3081-UNV

Abstract: Adding a methanizer to a GC-FID is an easy, effective, and cost-efficient way to analyze CO and CO2 at ppb levels. This article explains the technique and shares best practices for preventing problems and obtaining accurate results.

Residual Pesticides Analysis of Botanical Ingredients Using Gas Chromatography Triple Quadrupole Mass Spectrometry

Author(s): Riki Kitano1, Tairo Ogura1, Nicole Lock1, Robert Clifford1, Julie Kowalski2, Jack Cochran2, Dan Li2
1. Shimadzu Scientific Instruments, Inc. 2. Restek Corporation

Published By: Restek Corporation

Year of Publication: 2019

Link: www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FSAR3080-UNV

Abstract: Dietary supplements, which are consumed worldwide, are made from various botanical ingredients. To be safe from pesticides exposure, residual pesticides must be monitored by chromatographic instrumentation. Issues arise, however, due to the fact these botanical samples are dried and cause large interferences in the chromatography. This study shows that the modified QuEChERS method combined with GC-MS/MS achieves consistent pesticides monitoring in botanical ingredients.

Acknowledgment(s): Originally published by Shimadzu Corporation in collaboration with Restek Corporation.

Integrating the Analysis of Ultrashort-Chain PFAS: Method Development for Simultaneous Analysis of Ultrashort-Chain, Alternative, and Legacy PFAS

Author: Shun-Hsin Liang and Mike Chang

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAN3073-UNV

Abstract: A simple direct injection LC-MS/MS method was developed and evaluated for the simultaneous analysis of ultrashort-chain, alternative, and legacy per- and polyfluoroalkyl substances (PFAS) in various water samples. This method is recommended for labs wanting to use a single procedure to analyze compounds from all three PFAS categories in potable and non-potable waters.

PFAS LC Column Anatomy: Which Phase, Dimensions, and Particle Type Are Best?

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAR3069-UNV

Abstract: With the expansion of PFAS target analyte lists into shorter chain compounds, the need for better methods is growing. But, when developing new analytical procedures, which PFAS LC column is best? This article explores the impact of phase, dimensions, and particle types and provides options that ensure fast, accurate results.

Successful Strategies for the Analysis of EtG and EtS in Urine: Rugged Sample Preparation and Analysis Conditions for High-Throughput Labs

Author: Justin Steimling, Ravali Alagandula, and Frances Carroll

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFAR3061-UNV

Abstract: LC-MS/MS analysis of EtG and EtS is challenging due primarily to poor retention and resolution of EtG and EtS from matrix components. This article presents a foundation method that is useful for many samples and also demonstrates effective strategies for improving sensitivity and mitigating matrix effects.

Rapid, Simple 4.5-Minute Pyrrolizidine Alkaloids Analysis by LC-MS/MS

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFSS3064-UNV

Abstract: Pyrrolizidine alkaloid analysis is time consuming, with a typical run time of 15 minutes, and the acid digestion step can shorten analytical column lifetime. In contrast, this analysis using an acid-resistant Raptor ARC-18 column eluted the final compound in just 3.2 minutes with good peak shape and separation.

Analysis of Amphetamines by LC-MS/MS for High-Throughput Urine Drug Testing Labs

Author: Ravali Alagandula and Frances Carroll

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFAN3052-UNV

Abstract: Accurate analysis of d- and l-amphetamine and methamphetamine enantiomers can be achieved using chiral columns, but the method presented here provides a simpler, more cost-effective approach for high-throughput labs. Excellent separation of all enantiomers in urine was obtained in a fast, 7-min LC-MS/MS quantitative analysis on a Raptor C18 column with no interference from matrix components.

LC-MS/MS Analysis of 58 Antipsychotics and Antidepressants in Human Urine

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFSS3051-UNV

Abstract:

Simultaneous measurement of 58 antipsychotic and antidepressant drugs in human urine can be achieved with a simple sample preparation procedure and a fast 5.5-minute LC-MS/MS analysis on a Raptor Biphenyl column. This method provides accurate, high-throughput determinations and is suitable for both clinical and forensic monitoring.

Robust Analysis of Fatty Acids in Milk: An Independent Lifetime Evaluation of Rt-2560 GC Columns

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFAR3047-UNV

Abstract:

The analysis of fatty acids in milk fat is an important test and this challenging matrix was used by Eurofins Analytik GmbH to evaluate the stability of Rt-2560 columns. Consistent retention times and separations were achieved even after 225 injections, demonstrating the column’s robust performance.