Going to ExTech/ISSS 2016? Attend the Restek / CTC Analytics Workshop on #SPME Technology

SPME_CRMIn addition to being in booth #2C to discuss how Restek’s GC & LC columns and accessories, sample preparation, reference standards, and other chromatography solutions can benefit your lab, we are partnering with CTC Analytics to present a workshop on solid phase microextraction (SPME) technology. If you will be in Poland for ExTech/ISSS, we invite you to attend:

Sunday, July 3 / 10:00–13:00 / Faculty of Chemistry, Nicolaus Copernicus University, Toruń
Sample Preparation Workflow Automatization — Advances in SPME Technologies
Presenters: Gary Stidsen (Restek Corporation), Mevio Heierli (CTC Analytics)

Registration begins at 9:00

With patents for SPME fibers maturing, there are new opportunities to make improvements in SPME fiber polymers and fiber construction. This has led to improvements in automation technologies, allowing laboratories to be more efficient and improve data quality. This workshop will focus on SPME technology improvements and how new technologies are being used in automation to reduce manual sample prep and improve data quality. The following topics will be discussed:

a) SPME fiber improvements.
b) New SPME Arrow technology.
c) Moving from manual to automated integrated laboratory workflows.
d) Improving reproducibility and reliability through laboratory automation.

For more information, visit the ExTech/ISSS website at www.extech-isss2016.pl/workshops

A Fast Dilute-And-Shoot Method for Simultaneous 5-Hydroxyindoleacetic Acid (5-HIAA), Vanillylmandelic Acid (VMA), and Homovanillic Acid (HVA) LC-MS/MS Analysis in Human Urine

Author(s): Shun-Hsin Liang and Sue Steinike
Restek Corporation

Published By: Restek Corporation

Year of Publication: 2016

Link: http://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFAN2465-UNV

Abstract: In this partial validation study, we demonstrated the performance of a fast dilute-and-shoot LC-MS/MS method using a Raptor™ Biphenyl column for the simultaneous analysis of 5-hydroxyindoleacetic acid (5-HIAA), vanillylmandelic acid (VMA), and homovanillic acid (HVA) in human urine. Excellent results were obtained for linearity, accuracy, and precision. With this method, these serotonin and catecholamine metabolites can be measured in human urine with a 5-minute total analysis time. The analytical method is applicable to clinical labs that require a combination of fast analysis times and low-cost sample preparation procedures for 5-HIAA, VMA, and HVA using LC-MS/MS analysis.

Effects of Column Inner Diameter and Packed Bed Heterogeneities on Chromatographic Performance

Authors: Edward G. Franklin and Ty W. Kahler
Restek Corporation

Published By: LCGC North America

Year of Publication: 2016

Link: http://www.chromatographyonline.com/effects-column-inner-diameter-and-packed-bed-heterogeneities-chromatographic-performance

For the full issue, visit: http://images2.advanstar.com/PixelMags/lcgc-na/digitaledition/06-2016.html#18


In recent years, industry has been moving to columns with smaller and smaller inner diameters—moving from 4.6 and 3.0 mm i.d. columns to 2.1 mm, 1.0 mm, and even smaller. While small inner diameter columns have some clear advantages, they also bring challenges.  Reduction of extracolumn volumes must be given greater consideration by both customers and manufacturers. This installment of “Column Watch” focuses on the sources of band broadening within high performance liquid chromatography (HPLC) columns with an emphasis on eddy dispersion. The physical mechanisms of dispersion are discussed and a review of the current literature as it pertains to small inner diameter columns is presented.

The Practical Chemist: Calibration Part II – Evaluating Your Curves

Author: Amanda Rigdon
Restek Corporation

Published By: Cannabis Industry Journal

Year of Publication: 2016

Link: https://www.cannabisindustryjournal.com/column/calibration-part-ii-evaluating-your-curves/

Abstract: Despite the title, this article is not about weight loss – it is about generating valid analytical data for quantitative analyses. In the last installment of The Practical Chemist, I introduced instrument calibration and covered a few ways we can calibrate our instruments. Just because we have run several standards across a range of concentrations and plotted a curve using the resulting data, it does not mean our curve accurately represents our instrument’s response across that concentration range. In order to be able to claim that our calibration curve accurately represents our instrument response, we have to take a look at a couple of quality indicators for our curve data.


High-Performing SPME Fibers Now Available from Restek

SPME_CRMSolid phase microextraction (SPME) automated sample preparation reduces sample handling and solvent consumption, and it has many applications in environmental, food, clinical, and other industries. New Restek® PAL SPME fibers are high-performing fibers that meet or exceed the performance of other brands. Our reliable SPME fibers feature an aluminum hub that is more durable than plastic. These fibers are optimized for PAL system autosamplers and are compatible with most GC inlets. Restek SPME fibers are suitable for a wide range of analyte chemistries and sample matrices. Our SPME product line is continually expanding and currently includes SPME fibers for both polar and nonpolar target analytes across a wide range of molecular weights and volatilities.

Learn more at www.restek.com/SPME