Potency Analysis of Cannabis and Derivative Products: Part 2

Author: Rebecca Stevens

Restek Corporation

Published By: Cannabis Industry Journal

Year of Publication: 2016

Link: https://www.cannabisindustryjournal.com/column/potency-analysis-of-cannabis-and-derivative-products-part-2/

Abstract:

For potency analysis via HPLC, grinding/homogenization and alcohol extraction is a common sample prep technique for dried flower and extracts.

As mentioned in Part 1, the physiological effects of cannabis are mediated by a group of structurally related organic compounds known as cannabinoids. The cannabinoids are biosynthetically produced by a growing cannabis plant and Figure 1 details the biosynthetic pathways leading to some of the most important cannabinoids in plant material.

The analytical measurement of cannabinoids is important to ensure the safety and quality of cannabis as well as its extracts and edible formulations. Total cannabinoid levels can vary significantly between different cultivars and batches, from about 5% up to 20% or more by dry weight. Information on cannabinoid profiles can be used to tailor cultivars for specific effects and allows end users to select an appropriate dose.

Appropriate Instrumentation for the Chemical Analysis of Cannabis and Derivative Products: Part 1

Author: Rebecca Stevens

Restek Corporation

Published By: Cannabis Industry Journal

Year of Publication: 2016

Link: https://www.cannabisindustryjournal.com/column/appropriate-instrumentation-for-the-chemical-analysis-of-cannabis-and-derivative-products-part-1/

Abstract:

The introduction of a series of articles focusing on the applications of instruments for different types of chemical analyses.

Election Day 2016 resulted in historic gains for state level cannabis prohibition reform. Voters in California, Maine, Massachusetts and Nevada chose to legalize adult use of Cannabis sp. and its extracts while even traditionally conservative states like Arkansas, Florida, Montana and North Dakota enacted policy allowing for medical use. More than half of the United States now allows for some form of legal cannabis use, highlighting the rapidly growing need for high quality analytical testing.

For the uninitiated, analytical instrumentation can be a confusing mix of abbreviations and hyphenation that provides little obvious information about an instrument’s capability, advantages and disadvantages. In this series of articles, my colleagues and I at Restek will break down and explain in practical terms what instruments are appropriate for a particular analysis and what to consider when choosing an instrumental technique.

Highly Reproducible Detailed cis/trans FAMEs Analysis Ensured by New Optimized Rt-2560 Column Manufacturing and Application-Specific QC Test

Author(s): Kristi Sellers and Rebecca Stevens

Restek Corporation

Published By: Restek Corporation

Year of Publication: 2016

Link: http://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFAR2589-UNV

Abstract:
Even minor variations in manufacturing processes can potentially have detrimental effects on column-to-column reproducibility. As shown here, Rt-2560 GC columns produced using a newly updated and optimized manufacturing process exhibit high reproducibility and provide consistent performance for detailed cis/trans FAMEs analysis.

Rt-2560 Columns Ensure Accurate, Reliable AOAC 996.06 and AOCS Ce 1j-07 FAMEs Analysis

Author(s): Rebecca Stevens and Kristi Sellers

Restek Corporation

Published By: Restek Corporation

Year of Publication: 2016

Link: http://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFAR2588-UNV

Abstract:
Restek has optimized the manufacturing process and implemented a new, application-specific QC testing procedure for all new Rt-2560 columns (cat.# 13198). Here we demonstrate that, Rt-2560 columns produced using the optimized process exhibit excellent performance for both AOAC 996.06 and AOCS Ce 1j-07 FAMEs analysis and meet all method requirements.