A GC in Your Laptop

Author: Jaap de Zeeuw

Restek Corporation

Published By: The Analytical Scientist

Year of Publication: December 2018

Volume, Issue: Volume 71

Link: https://theanalyticalscientist.com/fileadmin/tas/pdf-versions/TAS_Issue_1218.pdf

Abstract:

Very few students get hands-on experience with a working gas chromatography system. In this article, Jaap de Zeeuw explains how we can overcome this problem using ProEZGC software. By simulating separations, this free, web-based software allows users to change any GC parameter and see how the separations are affected.

 

Analysis of d- and l-Amphetamine and Methamphetamine Enantiomers for High-Throughput Labs

Published By: Restek Corporation

Year of Publication: 2018

Link: https://www.restek.com/Development/cft_CFSS2974-UNV

Abstract: Accurate analysis of amphetamine and methamphetamine isomers can be achieved using chiral columns, but the method presented here provides a simpler, more cost-effective approach for high-throughput labs. Excellent separation of all isomers in urine was obtained in a fast, 7-min LC-MS/MS quantitative analysis on a Raptor C18 column with no interference from matrix components.

5.5 Minute LC-MS/MS Analysis of Mycotoxins in Peanut Powder

Published By: Restek Corporation

Year of Publication: 2018

Link: https://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFSS2971-UNV

Abstract:The method developed here provides a fast analysis of mycotoxins in peanut powder. Baseline separation of 12 FDA and EU regulated mycotoxins was achieved in a 5.5 minute analysis (7 minute total cycle time). This method can be applied to different matrices using either matrix-matched calibration or a stable isotope dilution assay. Sample throughput can be greatly increased by the short cycle time for each run.

Detailed Efficiency Analysis of Columns with a Different Packing Quality and Confirmation via Total Pore Blocking

Author: David S. Bell

Restek Corporation

Published By: Journal of Chromatography A

Year of Publication: December 2018

Volume, Issue:Volumes 1581–1582

Link: https://doi.org/10.1016/j.chroma.2018.10.052 

Abstract:

We report on a systematic study involving columns with a clearly different efficiency (4 distinct quality groups) obtained by packing the columns that were C18 bonded and end capped with a different carbon loading. Using B-term analysis (via peak parking) and theoretical models to estimate the magnitude of the Cm– and Cs-term contributions, it could be concluded that the difference in efficiency among the groups was entirely due to a difference in eddy dispersion. As such, the columns provided an ideal testing ground to verify how well the total pore blocking (TPB)-method can be used to probe differences in packing heterogeneity. In agreement with earlier literature observations, it turns out the TPB-method is much more sensitive to packing heterogeneities than the eddy dispersion (Heddy)-contribution measured under open-pore conditions via B- and C- term subtraction. Typically, differences in Heddy on the order of 0.1–0.5μm translate into a difference on the order of 0.5–2μm in the TPB mode. This confirms the TPB as a powerful technique to make very sensitive measurements of the homogeneity of packed beds.