Per-and polyfluorinated alkyl substances (PFAS) are often used in tubing and other liquid-contacting parts of an HPLC system, where they can leach into the mobile phase and interfere with sample analysis. This contamination is particularly problematic when analyzing at trace levels, such as at the ppt health advisory levels for drinking water. With many labs analyzing at single-digit ppt levels and striving for sub-ppt level detection, PFAS contamination from HPLC components can prevent accurate identification and quantitation of PFAS in samples. To eliminate this issue, Restek’s new PFAS delay column traps and “delays” system-related PFAS, preventing them from interfering with sample analysis. This delay column is a universal solution that can be used with any type of HPLC or UHPLC system up to 15,000 psi (1034 bar) and with any analytical column (fully porous or superficially porous).
Published By: Restek Corporation
Year of Publication: 2019
Using a PFAS delay column is an effective way to separate target PFAS in samples from interferences caused by PFAS contamination in the LC system. This article explains how the PFAS delay column can improve trace-level PFAS analysis by removing the impact of system-related interferences.
A new industry has bloomed, offering scientists a rare opportunity to build a field from the ground up, and Restek has already been helping.
In addition to Restek’s cannabis-specific products, applications, and support for cannabis testing labs, Ashlee Gerardi, Associate Business Development Manager at Restek, has joined the editorial advisory board of Cannabis Science and Technology. In her role, she will review articles submitted to the publication and provide additional insight and information on the cannabis testing industry by attending conferences and participating in trade association focus groups.
“I’m looking forward to advancing cannabis science and helping to ensure quality education continues to be found in the magazine,” she said. “Teaching this audience the fundamentals of chemistry and chromatography is vital to testing in this growing industry.”
Gerardi joined Restek in 2011, moving to Restek’s California office in 2013 as an R&D chemist. However, the demand for an additional business development manager was soon needed for the growing cannabis analysis industry, and Ashlee was eager to use her technical background and business knowledge to help Restek’s cannabis customers as an associate business development manager for the cannabis testing industry.
“Because the landscape is rapidly changing, one of the fastest-growing needs of the cannabis market is legitimacy. Our team at Restek provides consumables as well as testing solutions for product quality, potency, and safety analyses in the market,” she said.
Gerardi said the cannabis industry has a lot to offer adventurous scientists, as “there is still much of the cannabis plant that needs to be understood along with analytical challenges/pain points that remain to be solved,” adding that “Restek is supported by many knowledgeable scientists whom I interact with daily. Our team is constantly working to solve analytical pain points such as potency, terpenes, mycotoxins, residual solvents, and pesticide testing.”
By way of example, Ashlee noted that the recent November/December edition of Cannabis Science and Technology, Restek’s Justin Steimling, LC Solutions Applications Manager, wrote, “If product labels are to accurately reflect cannabinoid content, the complete sample composition must be considered in developing a robust and accurate analytical method.”
Gerardi said she keeps up with the wealth of cannabis knowledge through publications like Cannabis Science and Technology, but also through conferences and social media.
Gerardi still sees a lack of legitimacy in the cannabis market but says, “Restek is proud to have helped cannabis labs establish sound analytical practices from the beginning, and we will continue to be there for you every step of the way as the testing landscape changes.” In September 2019, she will attend the annual Cannabis Science Conference in Portland, OR, where she plans to give an oral presentation.
To read more from Ashlee about her experiences in the cannabis industry follow her on LinkedIn and follow Restek on Twitter, Facebook, and LinkedIn.
Before you go to MSACL U.S. 2019, visit our conference page to learn what we’ll be doing, to easily contact us with any questions you may have, and to access the conference’s website for additional event details.
Author: Shun-Hsin Liang and Frances Carroll
Published By: Restek Corporation
Year of Publication: 2019
The method established in this study provides accurate analysis of phosphatidylethanol (PEth) using a simple protein precipitation procedure and a fast 3.5 minute LC-MS/MS gradient run. Specific, sensitive analysis of PEth 16:0/18:1 in whole blood was obtained due to the unique selectivity and retention of the Raptor FluoroPhenyl column.
Chromatographers from Restek will be presenting at Waters’s upcoming seminars on April 2 in Greenbelt, MD, and April 4, in Morrisville, NC. These educational opportunities are aimed at scientists analyzing food and agricultural products using GC-MS. Topics include chromatographic theory, column selection, troubleshooting, and practical applications ranging from pesticides to mycotoxins analysis. Register today and join us for an outstanding technical training event focused on recent innovations for food testing.
Gas Chromatography Theory, Column Selection, and Troubleshooting
This course is a solid initiation into the fundamentals and best practices of this widely used technique. You will gain practical knowledge of the principals of gas chromatography, and GC column selection, as well as maintenance and troubleshooting. Chromatographic examples will be provided throughout the presentation.
View full program and register today.
Keep your organochlorine pesticide GCs up and running by protecting them against matrix components with superior sample cleanup. Resprep CarboPrep Plus SPE cartridges surpass traditional Florisil products in cleanup power for sample matrix compounds that cause active sites in GC inlets and columns, degrading pesticides and interrupting work due to failed calibration checks. For CarboPrep Plus cartridges, Restek uses a proprietary treatment to create an exceptionally clean carbon that exhibits consistent selectivity. The end result is a reliable sample preparation product that does not contribute interfering background signal and does not need to be evaluated lot to lot to see if elution volumes need to be adjusted. In addition, CarboPrep Plus cartridges are designed to use the same equipment, solvents, and solvent volumes as a traditional Florisil cleanup procedure, minimizing the impact of switching on sample prep labs while maximizing the performance benefit to analytical labs.
Before you go to Pittcon 2019, visit our conference page to learn what we’ll be doing, to easily contact us with any questions you may have, and to access the conference’s website for additional event details.
Restek Corporation, a leading independent developer and manufacturer of chromatography products, and LECO Corporation, a global leader in analytical instrumentation and mass spectrometers, are pleased to announce a recent expanded collaboration. This agreement will allow LECO customers access to a core set of Restek consumables—streamlining the customer’s setup and offering the convenience of one simplified combined package.
“For LECO customers, this is a great advantage to be able to purchase consumables directly with their instrument,” said Lorne Fell, PhD, Separation Science Product Manager. “We understand the importance of reliable consumables for accurate results and know that Restek products provide the utmost quality and ISO 9001 certification. We’re excited to partner with them on this venture.”
“LECO has been a strong partner for Restek for a number of years, and we are very pleased to further strengthen and expand our relationship globally,” said Becky Wittrig, PhD, Restek VP of Sales.