Improve Acrylamide Analysis with a Faster, Longer-Lasting LC Column

The porous graphitized carbon (PGC) columns typically used for acrylamide analysis by method EN 16618:2015 provide adequate retention of acrylamide and sufficient separation from matrix components, but they are subject to long run times and short column lifetimes. Switching to an Allure Acrylamide LC column is a better alternative: an Allure Acrylamide column used with a deuterated internal standard provides faster total analysis times and meets system suitability requirements longer.

Allure Acrylamide columns meet the EN method 1.7-minute retention time requirement with good separation from matrix components and a much shorter equilibration time. A per analysis savings of 2.5 minutes allows more samples to be analyzed per shift, significantly increasing lab output. In addition to faster run times, testing showed that the Allure Acrylamide column passed the 1.7-minute system suitability requirement for over twice as many injections as a typical PGC column.

Developed to withstand 100% aqueous mobile phases and elute coextracted matrix components rather than strongly retaining them, Restek Allure Acrylamide guard and analytical columns deliver the same robust performance injection to injection and column to column, making them a more reliable choice for acrylamide analysis, even in difficult food matrices like potato chips or coffee.

www.restek.com/acrylamide

Improve Acrylamide Analysis with a Long-Lasting LC Column and a Cost-Effective Internal Standard

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFAR3126-UNV

Abstract:The porous graphitized carbon (PGC) columns typically used for acrylamide analysis by method EN 16618.2015 provide adequate retention of acrylamide and sufficient separation from matrix components, but they are subject to short column lifetimes and the need for extensive sample preparation. Here, we demonstrate an approach using an Allure Acrylamide LC column and deuterated internal standard that provides faster total analysis times and meets system suitability requirements longer, allowing labs to significantly increase sample throughput.

Restek Donates Precision Measurement Tool to Local High School

 

Pictured from left are Devin Miller, Restek’s Matt Lininger, CMHS’s precision machining instructor Shan Packer, Ben Miller, Nicolas Ferrara, Cruise Woods, Michael Rupert, and Hunter Leeper.

Central Mountain High School’s precision machining instructor Shan Packer and Restek’s Matt Lininger prepare a demonstration of the optical comparator for students during Manufacturing Day on Oct. 4.

Central Mountain High School’s precision machining program got a bit more precise thanks to a donation from Restek.

The chromatography manufacturer donated a Horizontal Profile Projector as part of its October 4, Manufacturing Day celebrations at the high school in Mill Hall, PA. The tool will be used for vocational machining students to improve their skills in optical measurement.

“Industry donations play an important part in the personal growth of the students in the precision machining program,” said Shan Packer, CMHS’s precision machining program instructor. “Thanks to Restek, we can continue to train students to become young professionals.”

The donation was spearheaded by Matt Lininger, Senior Product Development Engineer at Restek, who saw it as an opportunity to give back to his alma mater. Lininger also currently serves on the Precision Machining Advisory Committee at CMHS.

“We got a new optical comparator in our shop at Restek, so I inquired if it was possible to donate the one we weren’t using,” Lininger said. “Restek was happy to help these young students, and I was excited to help the machining program at Central Mountain.”

Also known as an “optical comparator,” the Horizontal Profile Projector magnifies the silhouette of a machine part and allows machinists to measure the dimensions and geometry of the part against prescribed limits.

Recently, the machine program at CMHS moved into a larger facility and is expanding its program. Packer said the program acquired three new machines in the last 12 months through grants, but did not have an optical comparator until now.

Students will use the skills they develop with the optical comparator to take the “Material, Measurement, and Safety” certification test offered through the National Institute of Metalworking Skills. The MMS test is one of 11 certifications recognized by the both the Pennsylvania Department of Education and the Bureau of Technical Education as end-of-program assessments for precision machining.

CMHS is also collaborating with multiple career and technical centers, several area machine shops, and the PA Department of Labor to create a consortium to sponsor students in apprenticeship programs.

“This donation plays an important part in the personal growth of the students and makes a real impact on their interest in machining and the communities where they live,” Packer said.

Attain a More-Comprehensive Characterization of Cannabis Samples with Restek’s New Cannabicyclol (CBL) Reference Standard

Cannabicyclol (CBL) is formed through the photodegradation of cannabichromene (CBC). Levels are typically quite low, and the medicinal benefits of CBL are still being researched, but quantifying this compound in cannabis samples is crucial for obtaining a more-complete cannabinoids profile. Restek has just released a new CBL certified reference material (CRM) to further aid labs in the comprehensive characterization of cannabis: www.restek.com/catalog/view/54615

Restek’s new CBL standard is ideal for creating multipoint (5-point minimum suggested) calibration curves for LC analysis. With verified composition and stability, this prepared stock product eliminates the need for in-house standards preparation for greater convenience and lower labor requirements. As a U.S. DEA-exempted formulation, no additional customer permits or licensing are required to purchase within the U.S., and because it’s manufactured and QC tested in Restek’s ISO-accredited labs, this new CBL standard qualifies as a certified reference material (CRM) that satisfies your ISO requirements.

For CBL and other reference standards, Raptor LC columns, sample preparation products, and the expert consultation your cannabis lab needs, turn to www.restek.com/cannabis