Author(s): Shun-Hsin Liang
Published By: Restek Corporation
Year of Publication: 2015
Abstract: A rapid, accurate, and reproducible method was developed for high-throughput testing of nicotine, cotinine, trans-3’-hydroxycotinine, nornicotine, norcotinine, and anabasine in urine. Data show that a fast and highly efficient analysis of these basic compounds can be achieved with the Raptor™ Biphenyl column using standard, low pH, reversed-phase LC-MS mobile phases which are compatible with a variety of LC-MS instrumentation.