Developing New Methods for Pesticides in Dietary Supplements

Author(s): Julie Kowalski, Michelle Misselwitz, Jason Thomas,  Jack Cochran

Published By: Food Safety Magazine

Issue: February/March 2012

Year of Publication: 2012

Link: http://www.foodsafetymagazine.com/article.asp?id=3876&sub=sub1

Abstract: New requirements for dietary supplements to be manufactured under current Good Manufacturing Practices (cGMP) regulations have created a need for methods to detect pesticides in these complex, largely botanical products. QuEChERS offers a simple, cost-effective approach that can reduce matrix interferences as well as variation among technicians. Here we demonstrate a procedure that incorporates a QuEChERS extraction, cartridge solid-phase extraction (cSPE) cleanup and gas chromatography-time-of-flight mass spectrometry (GC-TOFMS), resulting in good recoveries for a wide range of pesticide chemistries in dandelion root powder.