The Effects of LC Particle Choice on Column Performance: Raptor 1.8 µm Superficially Porous Particles (SPP) for UHPLC Analyses

Published By: Restek Corporation

Year of Publication: 2017


Abstract: Superficially porous particles (commonly referred to as SPP or “core-shell” particles) have been proven to provide fast and efficient LC separations. These particles feature a solid, impermeable core enveloped by a thin, porous layer of silica that offers significantly higher efficiency and sensitivity than traditional fully porous particles (FPP). At launch, Raptor SPP LC columns were touted for their selectivity and for their ability to help customers achieve faster separations with their existing HPLC instruments. With the launch of Raptor 1.8 µm columns, this superior Raptor performance has been unleashed on your UHPLC analyses. But, what exactly does that mean? In this technical note, we will explore the benefits of using Raptor 1.8 µm LC columns in your UHPLC instrument with a focus on peak capacity, column lifetime, and selectivity.