High-Throughput LC-MS/MS Analysis of Phosphatidylethanol in Whole Blood

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Clinical-Forensic-Toxicology/cft_CFSS2936-UNV

Abstract: Accurate analysis of phosphatidylethanol (PEth) can be achieved with a simple protein precipitation procedure and a fast 3.5 minute LC-MS/MS gradient run. The method shown here utilizes a Raptor FluoroPhenyl column and provides a low-cost, high-throughput solution for labs monitoring PEth as a biomarker for alcohol consumption.