Author(s): David Bell, Landon Wiest, Shun-Hsin Liang, Dan Li
Published By: LCGC Asia Pacific
Issue: Volume 21, Issue 3
Year of Publication: 2018
Abstract: The use of superficially porous particles (SPPs) for modern high performance liquid chromatography (HPLC) is now very common. Initially, SPPs rose as an alternative to sub-2-µm fully porous particles (FPPs). In recent years, many column manufacturers have developed 2-µm and smaller SPP-based products. This article investigates the practical utility of these smaller SPP designs.