Analysis of d- and l-Amphetamine and Methamphetamine Enantiomers for High-Throughput Labs

Published By: Restek Corporation

Year of Publication: 2018

Link: https://www.restek.com/Development/cft_CFSS2974-UNV

Abstract: Accurate analysis of amphetamine and methamphetamine isomers can be achieved using chiral columns, but the method presented here provides a simpler, more cost-effective approach for high-throughput labs. Excellent separation of all isomers in urine was obtained in a fast, 7-min LC-MS/MS quantitative analysis on a Raptor C18 column with no interference from matrix components.