Improve Acrylamide Analysis with a Long-Lasting LC Column and a Cost-Effective Internal Standard

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Foods-Flavors-Fragrances/fff_FFAR3126-UNV

Abstract:The porous graphitized carbon (PGC) columns typically used for acrylamide analysis by method EN 16618.2015 provide adequate retention of acrylamide and sufficient separation from matrix components, but they are subject to short column lifetimes and the need for extensive sample preparation. Here, we demonstrate an approach using an Allure Acrylamide LC column and deuterated internal standard that provides faster total analysis times and meets system suitability requirements longer, allowing labs to significantly increase sample throughput.