QuEChERS: The Concept

Author(s): Julie Kowalski, Amanda Rigdon, and Jack Cochran
Restek Corporation

Published By: Separation Science

Issue: vol. 5, issue 8

Year of Publication: 2013

Link: For the full print issue, visit http://www.sepscience.com/docs/Bespoke/Editions/SepSci/Sepsci0813eu.pdf?utm_source=iContact&utm_medium=email&utm_campaign=eLearning%20Newsletter%20-%20Europe%20Sep%20Sci&utm_content=

Abstract: The original QuEChERS sample preparation methods were designed for pesticide residue analysis of high water-content foods, specifically fruits and vegetables. QuEChERS methods provide “just enough” sample preparation because highly selective and sensitive modern instrumentation does not require extremely clean samples. In the first two installments of this series (#1 and #2), official methods were reviewed, as well as considerations for method development. Adjustments to the original methods for some difficult commodities and pesticides were reviewed as well. This article will focus on QuEChERS metamorphosis into a concept. “QuEChERS” will be used as a broad term in this article to describe not only modified QuEChERS methods but also methods based on QuEChERS principles. The success of QuEChERS relates back to the attributes set forth by the originators; Quick, Easy, Cheap, Effective, Rugged and Safe. In addition to these benefits, great flexibility and quick method development have encouraged the expansion of QuEChERS from specific methods to generic techniques, and now to a sample preparation concept.