A GC in Your Laptop

Author: Jaap de Zeeuw

Restek Corporation

Published By: The Analytical Scientist

Year of Publication: December 2018

Volume, Issue: Volume 71

Link: https://theanalyticalscientist.com/fileadmin/tas/pdf-versions/TAS_Issue_1218.pdf#page=38


Very few students get hands-on experience with a working gas chromatography system. In this article, Jaap de Zeeuw explains how we can overcome this problem using ProEZGC software. By simulating separations, this free, web-based software allows users to change any GC parameter and see how the separations are affected.


Analysis of FAMEs in Biodiesel Fuel: Pro EZGC Modeling Software Ensures Proper Column Selection

Author: Katarina Oden

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Petroleum-Petrochemical/petro_PCAN2889-UNV

Abstract: Polar columns were evaluated for the analysis of fatty acids methyl esters (FAMEs) in finished B100 biodiesel according to method EN 14103 (2011). Using Restek’s Pro EZGC chromatogram modeler, a high cyano phase Rt-2330 column and a polyethylene glycol phase FAMEWAX column were compared. The modeling software predicted an unacceptable coelution between the internal standard (C19:0 FAME) and FAME C18:2 when using the Rt-2330 column. However, the modeler also predicted that the FAMEWAX column would separate all the compounds of interest, which was demonstrated empirically. In addition, the results on the FAMEWAX column showed excellent repeatability for both total FAMEs and the linolenic acid methyl ester component.

A Simple Way to Reduce Analysis Time in GC

Author: Jaap de Zeeuw

Published By: Restek Corporation

Year of Publication: 2018

Link: https://www.labcompare.com/10-Featured-Articles/350677-A-Simple-Way-to-Reduce-Analysis-Time-in-GC/


There are several ways to decrease analysis time in GC. Reducing analysis time depends on the separations between the peaks of interest. In the case of enough separation, some efficiency can be traded for speed by:

  1. Using a shorter column length
  2. Operating the column at a higher flow rate or using flow programming to elute late-eluting compounds.

If the same efficiency is required, options are to:

  1. Use a faster carrier gas, i.e., hydrogen instead of helium
  2. Use a shorter capillary with a smaller bore—this produces similar efficiency with shorter run times.

In all of the above situations, analysis time is also limited by the maximum temperature programming that is allowed for the instrument used.

Faster Semivolatiles Analysis with a Scaled-Down Method and GC Accelerator Kit

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAR2837-UNV


Scaling down GC-MS columns and conditions can result in faster semivolatiles analysis times and increased sample throughput, but only when done correctly. In this technical article we demonstrate how to scale an existing method on a traditional format (30 m, 0.25 mm ID, 0.25 µm df) arylene-type column down to a 20 m long, 0.15 mm ID, 0.15 µm df column. By using a properly scaled column and method along with a GC Accelerator oven insert kit, the same separation was achieved with a saving of six minutes per injection.

Get Equivalent GC-MS Results Faster with Restek’s GC Accelerator Kit and EZGC Method Translator

Published By: Restek Corporation

Year of Publication: 2018

Link: http://www.restek.com/Technical-Resources/Technical-Library/General-Interest/gen_GNAR2823-UNV


Have a reliable method, but need results faster? EZGC method translation software makes it easy to get an equivalent separation in less time. By moving to a shorter column and adopting the translated method conditions, you can significantly reduce your analysis time. Agilent users can further speed up their analyses by installing a GC Accelerator oven insert kit.

Cut GC Method Development and Optimization Time with EZGC Web Tools: Software Solutions to Hard Problems

Free Separation Science Webinar

Presenter: Jonathan Keim, Restek

Date: December 5, 2017

Time: 8 a.m. PST / 11 a.m. EST / 4 p.m. GMT / 5 p.m. CET

A recorded, on-demand version will be available to everyone who registers for the live broadcast.


Chromatographic laboratories face continual pressure to increase productivity while decreasing costs. With recent advances in available technology, additional flexibility in updated methods, and optimization of key instrument parameters, we can find valuable opportunities to save time and money. In this talk, we will share work showing how the EZGC suite of online tools can be used to improve gas chromatographic analyses quickly and effectively, without spending any time at the bench.

You will learn how the free software can be used to improve your analyses in ways such as: maintaining high quality separations with much shorter columns, optimizing your splitless valve time, switching carrier gases, and automating method development.


Register for this event and you will…

  • Be able to describe how the Pro EZGC chromatogram modeler can be used to accelerate method development.
  • Be able to define the best situations for using Pro EZGC chromatogram modeler.
  • Be able to state several situations where you should use the EZGC method translator to translate your run conditions.



Will Pro EZGC Chromatography Modeling Software Work For You? We Put It to the Test!

Published By: Restek Corporation

Year of Publication: 2017

Link: http://www.restek.com/Technical-Resources/Technical-Library/General-Interest/general_GNAR2714-UNV


When it comes to speeding up method development, Pro EZGC modeling software saves you time, materials, and a lot of frustration. This technical article puts Restek’s GC chromatogram simulator to the test and demonstrates how well it predicts actual experimental outcomes.

EZGC Online Tools Now in Multiple Languages

GC method development just got easier for scientists all around the globe.
Restek’s EZGC online method development tools are now available in English, Portuguese, Spanish, French, Italian, Dutch, German, Japanese, and Chinese languages. No matter where you are in the world, EZGC software lets you develop new GC methods in minutes directly from your desk and optimize or modify existing methods reliably and without guesswork. Increase your productivity with our free, easy-to-use EZGC online software—it saves time, increases certainty, and is now available in multiple languages.


Overview of Restek’s EZGC Online Tools
New Pro EZGC Chromatogram Modeler
This new and improved version of our popular EZGC chromatogram modeler for polymer capillary columns is just as simple to use as the original, but it has been updated and now offers advanced options that give you more control. Based on user feedback, the new Pro EZGC chromatogram modeler lets you do the following:
• Start with either the column you have or a column recommended by the program.
• Select compounds from our libraries or bring your own list.
• Target specific compounds for resolution.
• Alter the GC conditions to optimize your model quickly and easily.
• Repeatedly refine the temperature program.
• Switch carrier gases.
• Change the control method (constant flow, pressure, or linear velocity).
• View elution temperatures in the peak list.
• See results for multiple phases.

EZGC Method Translator and Flow Calculator
The EZGC method translator and flow calculator tools make it simple to switch carrier gases, change column dimensions or control parameters, or to optimize a method for speed or efficiency. Simply enter your method specifications and the program will return a full set of calculated method conditions that will provide similar chromatography. Use the EZGC method translator and flow calculator tool to optimize your analysis for speed so you can increase sample throughput!

Method Translation in Gas Chromatography: Get the Same Chromatogram when Changing Flow, Pressure Drop, Column Dimensions or Carrier Gas

Author: Jaap de Zeeuw, Chris English, Jack Cochran, Chris Nelson

Published By: Separation Science

Year of Publication: 2016

Link: http://www.sepscience.com/docs/Articles/Oct2016/Jaap_Method_Translation_in_GC.pdf


In gas chromatography there is often a need to optimize separations for the sake of resolution, analysis time or cost of analysis. This can be realized by using different column dimensions, different linear gas velocity, using a different detector or using a different carrier gas. If one wants to get the same peak elution order and the same chromatogram, one must make sure that the elution temperatures of the components are kept the same. This is only possible by adjusting the oven temperature programme. Read more to find out how you can achieve this desired result.

New Pro EZGC Chromatogram Modeler Propels Method Development Forward

pro_ezgc_crmRestek’s new and improved EZGC chromatogram modeler is just as simple to use as the original software, but it now offers advanced options for selecting phases, changing carrier gases and control parameters, further optimizing results, and much more. The software has been updated based on user feedback, allowing chromatographers to develop and optimize GC methods more efficiently and effectively than ever before.
The new Pro EZGC chromatogram modeler allows you to do the following:
• Start with either the column you have or a column recommended by the program.
• Select compounds from Restek’s libraries or bring your own list.
• Target specific compounds for resolution.
• Alter the GC conditions to optimize your model quickly and easily.
• Repeatedly refine the temperature program.
• Switch carrier gases.
• Change the control method.
• View elution temperatures in the peak list.
• See results for multiple phases.
This free, online software provides a customized, interactive model chromatogram that matches real-world chromatograms with exceptional accuracy. Users can zoom in, view chemical structures, and even overlay the mass spectra of coeluting compounds. The updated Pro EZGC chromatogram modeler is an easy, risk-free way to increase lab productivity through faster, more effective method development and optimization.