Webinar: How to Analyze Extended PFAS Lists Including Ultrashort-Chain (C2-C3) PFAS

Register today for this timely C&EN webinar about PFAS analysis and incorporating ultrashort-chain PFAS into an existing method for legacy and alternative compounds. Mike Chang, Global Environmental Market Business Development Manager at Restek, will discuss LC-MS/MS method development for C2 and C3 PFAS analysis and analytical methodologies for simultaneous chromatographic determination of ultrashort-chain, alternative, and legacy PFAS.

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Integrating the Analysis of Ultrashort-Chain PFAS: Method Development for Simultaneous Analysis of Ultrashort-Chain, Alternative, and Legacy PFAS

Author: Shun-Hsin Liang and Mike Chang

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAN3073-UNV

Abstract: A simple direct injection LC-MS/MS method was developed and evaluated for the simultaneous analysis of ultrashort-chain, alternative, and legacy per- and polyfluoroalkyl substances (PFAS) in various water samples. This method is recommended for labs wanting to use a single procedure to analyze compounds from all three PFAS categories in potable and non-potable waters.

PFAS LC Column Anatomy: Which Phase, Dimensions, and Particle Type Are Best?

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/env_EVAR3069-UNV

Abstract: With the expansion of PFAS target analyte lists into shorter chain compounds, the need for better methods is growing. But, when developing new analytical procedures, which PFAS LC column is best? This article explores the impact of phase, dimensions, and particle types and provides options that ensure fast, accurate results.

Eliminate the Impact of PFAS Instrument Contamination with a Restek PFAS Delay Column

Per-and polyfluorinated alkyl substances (PFAS) are often used in tubing and other liquid-contacting parts of an HPLC system, where they can leach into the mobile phase and interfere with sample analysis. This contamination is particularly problematic when analyzing at trace levels, such as at the ppt health advisory levels for drinking water. With many labs analyzing at single-digit ppt levels and striving for sub-ppt level detection, PFAS contamination from HPLC components can prevent accurate identification and quantitation of PFAS in samples. To eliminate this issue, Restek’s new PFAS delay column traps and “delays” system-related PFAS, preventing them from interfering with sample analysis. This delay column is a universal solution that can be used with any type of HPLC or UHPLC system up to 15,000 psi (1034 bar) and with any analytical column (fully porous or superficially porous).

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Eliminate the Impact of Instrument-Related PFAS Interferences by Using a Delay Column

Published By: Restek Corporation

Year of Publication: 2019

Link: https://www.restek.com/Technical-Resources/Technical-Library/Environmental/enviro_EVAR3001-UNV


Using a PFAS delay column is an effective way to separate target PFAS in samples from interferences caused by PFAS contamination in the LC system. This article explains how the PFAS delay column can improve trace-level PFAS analysis by removing the impact of system-related interferences.