Impact of GC Parameters on the Separation Part 6: Choice of Carrier Gas and Linear Velocity

Author(s): Jaap de Zeeuw
Restek Corporation

Published By: Separation Science

Year of Publication: 2015

Link:  http://www.sepscience.com/Information/Archive/All-Articles/4188-/Impact-of-GC-Parameters-on-The-Separation-Part-6–Choice-of-Carrier-Gas-and-Linear-Velocity

Abstract: In part 1–5 of this series, we focused on the selection of the column dimensions and stationary phase. We also saw that temperature has a big impact on the chromatography. The last two factors, which are somewhat related, are the choice of carrier gas and the setting of linear gas velocity.

Impact of GC Parameters on the Separation Part 5: Choice of Column Temperature

Author(s): Jaap de Zeeuw
Restek Corporation

Published By: Separation Science

Year of Publication: 2015

Link: http://www.sepscience.com/Information/Archive/All-Articles/3839-/Impact-of-GC-Parameters-on-The-Separation—Part-5-Choice-of-Column-Temperature

Abstract: In parts 1, 2, 3 and 4 of this series we focused on the selection of stationary phase, column length, ID, and the film thickness. Besides the column specific parameters, there are three non-column specific parameters that impact the separation. These are the type of carrier gas, its linear velocity, and the temperature of the column. Here we look into the effects of temperature on separations.

Impact of GC Parameters on the Separation Part 4: Choice of Film Thickness

Author(s): Jaap de Zeeuw
Restek Corporation

Published By: Separation Science

Year of Publication: 2014

Link: https://www.restek.com/pdfs/Impact-of-GC-Parameters_Part4.pdf

Abstract: In parts 1, 2, and 3 of this series, we focused on the selection of stationary phase, column length, and internal diameter. The stationary phase is also deposited as a film or a layer, which is the fourth parameter, and we need to understand its impact. The thickness of the layer determines the amount of the stationary phase that is present in the capillary. Retention is directly related to the amount of the stationary phase; thicker films equal more retention. When do we choose thin or thick films and how do they impact the chromatography? Changing film thickness will impact several parameters: retention, loadability, bleed, efficiency, and even inertness.

Impact of GC Parameters on the Separation Part 3: Choice of Column Length

Author(s): Jaap de Zeeuw
Restek Corporation

Published By: Separation Science

Year of Publication: 2014

Link: http://www.sepscience.com/Information/Archive/All-Articles/3352-/Impact-of-GC-Parameters-on-The-Separation-Part-3-Choice-of-Column-Length

For the full print issue, visit http://www.sepscience.com/docs/Articles/Oct2014/SepSci1014_NA.pdf?utm_source=iContact&utm_medium=email&utm_campaign=eLearning%20Newsletter%20-%20North%20America%20Sep%20Sci&utm_content=

Abstract: In Parts 1 and 2 of this series, we focused on the selection of stationary phase and looked at different applications for using different internal diameters. Capillary columns are also available in different lengths. Here we look at the third parameter: column length. What is the impact of column length on the separation? If the length is changed, what do I have to do to get the results that I anticipate?

Impact of GC Parameters on the Separation Part I: Choice of the Stationary Phase

Author(s): Jaap de Zeeuw
Restek Corporation

Published By: Separation Science

Issue: vol. 6, issue 2

Year of Publication: 2014

For the full print issue, visit http://www.sepscience.com/docs/Bespoke/Editions/SepSci/SepSci022014eu.pdf

Abstract: In this series, we will discuss the impact of different parameters on the actual separation. We will do this by discussing how they impact and then explain the impact by some practical examples. In GC there are seven important parameters that we can choose to get a separation. All parameters have an impact and selection of a certain parameter has an impact on the separation.