Nitrosamines in Drinking Water on Rxi-624Sil MS by Modified EPA Method 521 Utilizing CSR-LVSI

GC_EV1286

	Peaks
1.	N-Nitrosodimethylamine-d6
2.	N-Nitrosodimethylamine
3.	N-Nitrosomethylethylamine
4.	N-Nitrosodiethylamine
5.	N-Nitrosodipropylamine-d14
6.	N-Nitrosodipropylamine
7.	N-Nitrosopyrrolidine
8.	N-Nitrosopiperidine
9.	N-Nitrosodibutylamine

Injection
Column	Rxi-624Sil MS, 30 m, 0.25 mm ID, 1.40 µm (cat.# 13868)
	using Rxi guard column 5 m, 0.25 mm ID (cat.# 10029)
	with universal Press-Tight connectors (cat.# 20429)
Standard/Sample	N-Nitrosodimethylamine-d6 (cat.# 33910)
	N-Nitrosodi-n-propylamine-d14 (cat.# 33911)
	Nitrosamine calibration mix, method 521 (cat.# 31898)
Diluent:	Dichloromethane
Conc.:	10 ng/mL
Inj. Vol.:	10 µL splitless (hold 1 min)
Liner:	Premium 4 mm single taper w/wool (cat.# 23303.5)
Inj. Temp.:	250 °C
Purge Flow:	80 mL/min
Oven
Oven Temp.:	38 °C (hold 1 min) to 160 °C at 12 °C/min to 200 °C at 5 °C/min (hold 1 min)
Carrier Gas	He, constant flow
Flow Rate:	1.4 mL/min

Detector

Agilent 5975C

SIM Program:

Group	Start Time (min)	Ion(s) (m/z)	Dwell (ms)
1	6.9	80, 74, 46, 43, 42	23
2	7.9	88, 56, 43, 42	30
3	8.9	102, 56, 44, 42	30
4	10	130, 78, 70, 58, 46, 43, 42	15
5	12.05	100, 68, 42, 41	30
6	14.5	158, 116, 84, 57, 41	23

Transfer Line Temp.:

280 °C

Analyzer Type:

Quadrupole

Source Temp.:

230 °C

Quad Temp.:

150 °C

Solvent Delay Time:

6.9 min

Tune Type:

BFB

Ionization Mode:

EI

Instrument

Agilent 7890A GC & 5975C MSD

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