Statins on Raptor ARC-18 (1.8 μm) by LC-MS/MS

LC_CF0710

	Peaks	t_R (min)	Conc. (ng/mL)	Precursor Ion	Product Ion	ESI Mode
1.	Pitavastatin	0.672	0.1	422.20	290.25	+
2.	Pravastatin	0.805	5	423.25	321.20	-
3.	Rosuvastatin	1.178	1	482.25	258.30	+
4.	Cerivastatin	1.385	0.1	460.30	356.30	+
5.	Fluvastatin	1.639	5	412.25	224.25	+
6.	Atorvastatin	1.713	1	559.30	440.20	+
7.	Mevastatin	1.964	1	413.15	311.35	+
8.	Lovastatin	2.129	1	427.15	325.25	+
9.	Simvastatin	2.316	1	441.25	325.40	+

Pravastatin is in negative mode

Column

Raptor ARC-18 (cat.# 9314232)

Dimensions:

30 mm x 2.1 mm ID

Particle Size:

1.8 µm

Temp.:

40 °C

Standard/Sample

Diluent:

75:25 Water:acetonitrile

Conc.:

0.1-5 ng/mL

Inj. Vol.:

1 µL

Mobile Phase

A:

0.1% Formic acid in water

B:

0.1% Formic acid in acetonitrile

Time (min)	Flow (mL/min)	%A	%B
0.00	0.7	75	25
2.50	0.7	25	75
2.80	0.7	25	75
2.81	0.7	75	25
3.50	0.7	75	25

Detector	MS/MS
Mode:	MRM
Instrument	UHPLC

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