Beta Blockers on Raptor Biphenyl

LC_GN0550

	Peaks	t_R (min)	Precusor Ion	Product Ion
1.	Atenolol	1.07	267.3	145.1
2.	Pindolol	1.39	249.2	116.1
3.	Metoprolol	1.63	268.3	116.1
4.	Labetalol	1.76	329.3	162.1
5.	Oxeprenolol	1.82	266.3	72.1
6.	Propranolol	1.88	260.3	116.1

Column

Raptor Biphenyl (cat.# 9309A5E)

Dimensions:

50 mm x 3.0 mm ID

Particle Size:

2.7 µm

Temp.:

40 °C

Sample

Diluent:

Initial mobile phase

Conc.:

5 ng/mL

Inj. Vol.:

1 µL

Mobile Phase

A:

5 mM Ammonium formate + 0.1% formic acid in water

B:

5 mM Ammonium formate + 0.1% formic acid in methanol

Time (min)	Flow (mL/min)	%A	%B
0.00	0.6	95	5
2.00	0.6	5	95
2.01	0.6	95	5
3.00	0.6	95	5

Detector	Waters Xevo TQ-S
Ion Mode:	ESI+
Instrument	Waters

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