Raptor Biphenyl LC Columns (USP L11)

Ideal for bioanalytical testing applications like drug and metabolite analyses.
Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries.
Limits ionization suppression and allows simple, MS-friendly mobile phases.
Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica.

Learn more about Raptor 1.8 µm particles.

Technical Literature: Raptor Biphenyl LC Columns

Ordering Notes

Certificates of analysis for new Restek LC columns are now provided electronically. To view and download, visit www.restek.com/documentation then enter your cat.# and serial #.

Documentation and Instructions Sheets

Instruction Sheet: Restek Liquid Chromatography (LC) Columns - Usage & Care

Raptor Biphenyl LC Columns (USP L11)

Chromatograms

Additional Product Details

Product Options

Not sure which Restek product is the best for your analysis? Consult a Technical Specialist

Catalog #					Clear All
9309212	2.1 mm	100 mm	1.8 µm	ea.	Select Deselect
Catalog # 9309212 ID 2.1 mm Length 100 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, UHPLC, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk.
930921E	3.0 mm	100 mm	1.8 µm	ea.	Select Deselect
Catalog # 930921E ID 3.0 mm Length 100 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk. Raptor Biphenyl, UHPLC, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
9309232	2.1 mm	30 mm	1.8 µm	ea.	Select Deselect
Catalog # 9309232 ID 2.1 mm Length 30 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, UHPLC, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk.
9309252	2.1 mm	50 mm	1.8 µm	ea.	Select Deselect
Catalog # 9309252 ID 2.1 mm Length 50 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, UHPLC, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk.
930925E	3.0 mm	50 mm	1.8 µm	ea.	Select Deselect
Catalog # 930925E ID 3.0 mm Length 50 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk. Raptor Biphenyl, UHPLC, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
9309262	2.1 mm	150 mm	1.8 µm	ea.	Select Deselect
Catalog # 9309262 ID 2.1 mm Length 150 mm Particle Size 1.8 µm Units ea. Note For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, UHPLC, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. UltraShield UHPLC PreColumn Filter, 0.2 µm frit, 5-pk.
9309512	2.1 mm	100 mm	5 µm	ea.	Select Deselect
Catalog # 9309512 ID 2.1 mm Length 100 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk.
9309515	4.6 mm	100 mm	5 µm	ea.	Select Deselect
Catalog # 9309515 ID 4.6 mm Length 100 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk.
930951E	3.0 mm	100 mm	5 µm	ea.	Select Deselect
Catalog # 930951E ID 3.0 mm Length 100 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
930953E	3.0 mm	30 mm	5 µm	ea.	Select Deselect
Catalog # 930953E ID 3.0 mm Length 30 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
9309552	2.1 mm	50 mm	5 µm	ea.	Select Deselect
Catalog # 9309552 ID 2.1 mm Length 50 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk.
9309555	4.6 mm	50 mm	5 µm	ea.	Select Deselect
Catalog # 9309555 ID 4.6 mm Length 50 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk.
930955E	3.0 mm	50 mm	5 µm	ea.	Select Deselect
Catalog # 930955E ID 3.0 mm Length 50 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
9309562	2.1 mm	150 mm	5 µm	ea.	Select Deselect
Catalog # 9309562 ID 2.1 mm Length 150 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk.
9309565	4.6 mm	150 mm	5 µm	ea.	Select Deselect
Catalog # 9309565 ID 4.6 mm Length 150 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk.
930956E	3.0 mm	150 mm	5 µm	ea.	Select Deselect
Catalog # 930956E ID 3.0 mm Length 150 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk.
9309575	4.6 mm	250 mm	5 µm	ea.	Select Deselect
Catalog # 9309575 ID 4.6 mm Length 250 mm Particle Size 5 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules Raptor Biphenyl, 5 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk.
9309A12	2.1 mm	100 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A12 ID 2.1 mm Length 100 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A15	4.6 mm	100 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A15 ID 4.6 mm Length 100 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A1E	3.0 mm	100 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A1E ID 3.0 mm Length 100 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A32	2.1 mm	30 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A32 ID 2.1 mm Length 30 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A35	4.6 mm	30 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A35 ID 4.6 mm Length 30 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A3E	3.0 mm	30 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A3E ID 3.0 mm Length 30 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A52	2.1 mm	50 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A52 ID 2.1 mm Length 50 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A55	4.6 mm	50 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A55 ID 4.6 mm Length 50 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A5E	3.0 mm	50 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A5E ID 3.0 mm Length 50 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A62	2.1 mm	150 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A62 ID 2.1 mm Length 150 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 2.1 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A65	4.6 mm	150 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A65 ID 4.6 mm Length 150 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 4.6 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules
9309A6E	3.0 mm	150 mm	2.7 µm	ea.	Select Deselect
Catalog # 9309A6E ID 3.0 mm Length 150 mm Particle Size 2.7 µm Units ea. Pore Size 90 Å Product Name Raptor Biphenyl Often Purchased with: Raptor Biphenyl, 2.7 µm, 5 x 3.0 mm EXP Guard Column Cartridge, 3-pk. EXP Direct Connect Holder for EXP Guard Cartridges, Includes fitting & ferrules

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times with existing HPLC and UHPLC instrumentation. Learn more about Raptor LC columns at www.restek.com/raptor

The innovative Biphenyl is Restek's most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries. As a result, the rugged Raptor Biphenyl column is extremely useful for fast separations in bioanalytical testing applications like drug and metabolite analyses, especially those that require a mass spectrometer (MS). Increasing retention of early-eluting compounds can limit ionization suppression, and the heightened selectivity helps eliminate the need for complex mobile phases that are not well suited for MS detection.

Stationary Phase Category: Phenyl (L11)
Ligand Type: Biphenyl
Particle: 1.8 µm, 2.7 µm, or 5 µm superficially porous particle (SPP or “core-shell” particle) silica
Pore Size: 90 Å
Carbon Load: 7% (1.8 µm); 7% (2.7 μm); 5% (5 μm)
End-Cap: yes
Surface Area: 125 m²/g (1.8 µm); 130 m²/g (2.7 µm); or 100 m²/g (5 µm)
Recommended Usage:
pH Range: 2.0 to 8.0
Maximum Temperature: 80 °C
Maximum Pressure: 1034 bar/15,000 psi* (1.8 μm); 600 bar/8700 psi (2.7 μm); 400 bar/5800 psi (5 μm)

* For maximum lifetime, recommended maximum pressure for 1.8 μm particles is 830 bar/12,000 psi.

Properties:

Increased retention for dipolar, unsaturated, or conjugated solutes.
Enhanced selectivity when used with methanolic mobile phase.
Ideal for increasing sensitivity and selectivity in LC-MS analyses.

Switch to a Biphenyl column when:

Limited selectivity is observed on a C18.
You need to increase retention of hydrophilic aromatics.

Similar Phases

Supelco/Millipore Sigma: Ascentis Express Biphenyl (2.7 µm)

Phenomenex: Kinetex Biphenyl

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Raptor Biphenyl LC Columns (USP L11)

Catalog #

Catalog # 9309212

Catalog # 930921E

Catalog # 9309232

Catalog # 9309252

Catalog # 930925E

Catalog # 9309262

Catalog # 9309512

Catalog # 9309515

Catalog # 930951E

Catalog # 930953E

Catalog # 9309552

Catalog # 9309555

Catalog # 930955E

Catalog # 9309562

Catalog # 9309565

Catalog # 930956E

Catalog # 9309575

Catalog # 9309A12

Catalog # 9309A15

Catalog # 9309A1E

Catalog # 9309A32

Catalog # 9309A35

Catalog # 9309A3E

Catalog # 9309A52

Catalog # 9309A55

Catalog # 9309A5E

Catalog # 9309A62

Catalog # 9309A65

Catalog # 9309A6E

Chromatograms

Additional Product Details