Silylation Derivatization Reagents

Replace active hydrogen, reducing polarity and making the compounds more volatile.
Increase stability of derivatives.

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Silylation Derivatization Reagents

Compounds

Chromatograms

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Catalog #				Clear All
35600	MSTFA (N-methyl-N-trimethylsilyltrifluoroacetamide)	24589-78-4	10-pk. (10x1 g)	Select Deselect
Catalog # 35600 Product Name MSTFA (N-methyl-N-trimethylsilyltrifluoroacetamide) CAS Number 24589-78-4 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMSTFA-0-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35601	MSTFA (N-methyl-N-trimethylsilyltrifluoroacetamide)	24589-78-4	25 g vial	Select Deselect
Catalog # 35601 Product Name MSTFA (N-methyl-N-trimethylsilyltrifluoroacetamide) CAS Number 24589-78-4 Units 25 g vial Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMSTFA-0-25 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35602	MSTFA w/1% TMCS (N-methyl-N-trimethylsilytrifluoroacetamide w/1% trimethylchlorosilane)	24589-78-4	10-pk. (10x1 g)	Select Deselect
Catalog # 35602 Product Name MSTFA w/1% TMCS (N-methyl-N-trimethylsilytrifluoroacetamide w/1% trimethylchlorosilane) CAS Number 24589-78-4 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMSTFA-1-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35603	MSTFA w/1% TMCS (N-methyl-N-trimethylsilytrifluoroacetamide w/1% trimethylchlorosilane)	24589-78-4	25 g vial	Select Deselect
Catalog # 35603 Product Name MSTFA w/1% TMCS (N-methyl-N-trimethylsilytrifluoroacetamide w/1% trimethylchlorosilane) CAS Number 24589-78-4 Units 25 g vial Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMSTFA-1-25 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35604	BSTFA (N,O-bis[trimethylsilyl]trifluoroacetamide)	25561-30-2	10-pk. (10x1 g)	Select Deselect
Catalog # 35604 Product Name BSTFA (N,O-bis[trimethylsilyl]trifluoroacetamide) CAS Number 25561-30-2 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SBSTFA-0-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35605	BSTFA (N,O-bis[trimethylsilyl]trifluoroacetamide)	25561-30-2	25 g vial	Select Deselect
Catalog # 35605 Product Name BSTFA (N,O-bis[trimethylsilyl]trifluoroacetamide) CAS Number 25561-30-2 Units 25 g vial Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SBSTFA-0-25 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35606	BSTFA w/1% TMCS (N,O-bis[trimethylsilyltrifluoroacetamide] w/1% trimethylchlorosilane)	25561-30-2	10-pk. (10x1 g)	Select Deselect
Catalog # 35606 Product Name BSTFA w/1% TMCS (N,O-bis[trimethylsilyltrifluoroacetamide] w/1% trimethylchlorosilane) CAS Number 25561-30-2 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SBSTFA-1-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35607	BSTFA w/1% TMCS (N,O-bis[trimethylsilyltrifluoroacetamide] w/1% trimethylchlorosilane)	25561-30-2	25 g vial	Select Deselect
Catalog # 35607 Product Name BSTFA w/1% TMCS (N,O-bis[trimethylsilyltrifluoroacetamide] w/1% trimethylchlorosilane) CAS Number 25561-30-2 Units 25 g vial Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SBSTFA-1-25 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35608	MTBSTFA w/1% TBDMCS (N-methyl-N[tert-butyldimethylsilyl trifluoroacetamide] w/1% tert-butyldimethylchlorosilane)	77377-52-7	10-pk. (10x1 g)	Select Deselect
Catalog # 35608 Product Name MTBSTFA w/1% TBDMCS (N-methyl-N[tert-butyldimethylsilyl trifluoroacetamide] w/1% tert-butyldimethylchlorosilane) CAS Number 77377-52-7 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMTBSTFA-1-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35610	MTBSTFA w/1% TBDMCS (N-methyl-N[tert-butyldimethylsilyl trifluoroacetamide] w/1% tert-butyldimethylchlorosilane)	77377-52-7	25 g vial	Select Deselect
Catalog # 35610 Product Name MTBSTFA w/1% TBDMCS (N-methyl-N[tert-butyldimethylsilyl trifluoroacetamide] w/1% tert-butyldimethylchlorosilane) CAS Number 77377-52-7 Units 25 g vial Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT SMTBSTFA-1-25 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us
35611	TMCS (trimethylchlorosilane)	75-77-4	10-pk. (10x1 g)	Select Deselect
Catalog # 35611 Product Name TMCS (trimethylchlorosilane) CAS Number 75-77-4 Units 10-pk. (10x1 g) Certified Reference Material (CRM) No Min Shelf Life on Ship Date* 12 months Shipping Conditions Ambient Storage Temperature Ambient Similar To UCT STMCS-0-1 For more information about storage and shipment temperatures, see our FAQ. *Have specific minimum (min.) shelf- life requirements? Contact us

Silylation is the most widely used derivatization procedure for sample analysis by GC. In silylation, an active hydrogen is replaced by an alkylsilyl group such as trimethylsilyl (TMS) or tert-butyldimethylsilyl (tert-BDMS). Silyl derivatives are more volatile, less polar, and more thermally stable. As a result, GC separation is improved, and detection is enhanced.

Both TMS and tert-BDMS reagents are suitable for a wide variety of compounds and can be used for many GC applications. (Note that silylation reagents are generally moisture-sensitive and must be sealed to prevent deactivation.)