USLC Columns—Ultra Selective Liquid Chromatography
Choose Columns Fast. Develop Methods Faster.
- Represents the widest range of reversed phase selectivity available, with just 4 stationary phases: Aqueous C18, IBD, Biphenyl, and PFP Propyl.
- Simplifies column choice for fast, effective method development.
- Offers greater control to more easily resolve closely eluting peaks.
- Maximizes column screening efficiency by ensuring orthogonality between analytical runs.
- Fits universally on any HPLC or UHPLC instrumentation.
Selectivity is the most influential factor affecting peak separation, or resolution. Restek Ultra Selective Liquid Chromatography (USLC) technology is the directed application of orthogonal selectivity to help the practicing chromatographer develop methods more efficiently and more effectively. The Restek USLC column set offers the widest range of selectivity in the industry using just 4 unique stationary phases—Aqueous C18, IBD, Biphenyl, and PFP Propyl—to simplify phase selection.
Restek USLC columns are available on two silica lines to accommodate any instrument platform or chromatographic application. Pinnacle DB columns (1.9 µm) feature base deactivated silica and are recommended for scalable HPLC and UHPLC analyses. Ultra columns (3 and 5 µm) use highest purity silica and are well suited for traditional HPLC analyses.
USLC Columns Put the Right Tools in Your LC Method Development Toolbox - Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection
Column selectivity has the most significant influence on chromatographic peak separation, or resolution, so choosing the right column can greatly speed up HPLC and UHPLC method development. In this article, we discuss column choice and identify a set of just 4 stationary phasesRestek’s USLC column setthat encompasses the widest range of reversed phase selectivity available today.
Column choice is a critical factor in successfully transferring methods between UHPLC and HPLC. Here, we discuss the column qualities that contribute to the successful integration of UHPLC technology.
Novel column chemistries are a simple change in an already budgeted consumable that can lead to optimized and more reliable methods—giving a fast return on a minimal investment.
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Restek USLC columns offer the widest range of selectivity available and are an integral part of successful method development. Ideal for column switching systems, these columns provide orthogonal separations to create optimal resolution and robust methods—all in a 4-column set.
USLC columns and this guide will help you easily choose the right stationary phase to target nearly any analyte in reversed phase or HILIC method development. It will also help you adjust your mobile phase to further improve results without guesswork or wasted time.